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1. Analysis of Conformational Continuum and Free-energy Landscapes from Manifold Embedding of Single-particle Cryo-EM Ensembles of Biomolecules

Seitz, Evan Elliott
2022
Theses
Molecular biologyBiomoleculesElectron microscopy—Data processingMachine learningRiemannian manifoldsGibbs' free energyPath analysis (Statistics)RibosomesCOVID-19 (Disease)--Data processing

2. Bacterial Genome Engineering with CRISPR RNA-Guided Transposons

Vo, Phuc Hong
2022
Theses
Molecular biologyMicrobiologyBacterial geneticsBacterial genomesTherapeuticsEscherichia coli--GeneticsTransposonsDNACRISPR (Genetics)

3. Characterization of pathogenic BicD2 mutations in vitro and in vivo.

Yi, Julie Young Joo
2022
Theses
CytologyMolecular biologyNeurosciencesMicrotubulesEukaryotic cellsDyneinMutagenesisKinesin

4. Single-cell Analysis of Alopecia Areata

Lee, Yoo Jin
2022
Theses
ImmunologyMolecular biologyAlopecia areata--Animal modelsMiceBaldnessPathologyCytokinesLymphocytesNucleotide sequenceCancer--Treatment

5. A p53-independent role for MDM2-MDMX in cell cycle progression

Klein, Alyssa Michelle
2021
Theses
CytologyMolecular biologyBiochemistryCancerMutation

6. Discovery of Novel Ferroptosis Regulators Using Genetic and Lipidomic Analyses

Bezjian, Carla Tara
2021
Theses
CytologyMolecular biologyBiochemistryCell deathGenetic regulationPhospholipids

7. Epitranscriptomic Alterations in Alzheimer’s Disease: The Role of MicroRNA Methylation in the Regulation of Tau Proteostasis

Kim, Yoon Anna
2021
Theses
NeurosciencesPathologyMolecular biologyAlzheimer's disease--Genetic aspectsMicroRNAMethyltransferasesNervous system--DegenerationPhosphorylationDrosophila--GeneticsRats--GeneticsMice--Genetics

8. Function and Regulation of ALS/FTD-associated RNA Binding Protein FUS

Tsai, Yueh-Lin
2021
Theses
BiologyCytologyMolecular biologyRNA-protein interactionsAmyotrophic lateral sclerosisDementia

9. Leveraging the potential of human iPSC-derived cardiomyocytes: From modeling congenital heart disease to treating myocardial infarction

Liu, Bohao
2021
Theses
Biomedical engineeringMolecular biologyMedicineMyocardial infarctionCongenital heart diseaseHeart cellsStem cellsHuman beings

10. Mutagenic Repair Outcomes of DNA Double-Strand Breaks

Al-Zain, Amr M.
2021
Theses
BiologyMolecular biologyDouble-stranded RNACancer--EtiologyCancer--Genetic aspectsGenomesMutagenesis

11. Neurometabolic alterations after traumatic brain injury: Links to mitochondria-associated ER membranes and Alzheimer’s disease

Agrawal, Rishi Raj
2021
Theses
Molecular biologyCytologyNeurosciencesBrain--Wounds and injuriesAlzheimer's disease--EtiologyMitochondrial membranes

12. Non-apoptotic Caspase-8 Signaling Mediates Retinal Angiogenesis

Johnson, Kendra Vincia
2021
Theses
NeurosciencesCytologyMolecular biologyRetina--DiseasesRetina--Blood-vesselsNeovascularizationRetinal degeneration--Animal models

13. Phenotypic dissection and therapeutic manipulation of cell differentiation programs in the salivary gland epithelium and human Adenoid Cystic Carcinomas

Viragova, Sara
2021
Theses
CytologyMolecular biologySalivary glandsEpithelium--DiseasesAdenoid cystic carcinomaCancer--Radiotherapy

14. Pparg Drives Luminal Differentiation and Luminal Tumor Formation in the Urothelium

Tate, Tiffany
2021
Theses
OncologyCytologyMolecular biologyUrinary organsBladder--CancerBasal cell carcinoma

15. Spatially determined olfactory receptor choice is regulated by Nfi-dependent heterochromatin silencing and genomic compartmentalization

Bashkirova, Elizaveta Vladimirovna
2021
Theses
Molecular biologyHeterochromatinOlfactory receptorsOlfactory receptor genes

16. Stress and Rab35 modulate Alzheimer’s disease-related protein trafficking

Zhuravleva, Viktoriya
2021
Theses
NeurosciencesBiologyMolecular biologyAlzheimer's disease--ResearchStress (Physiology)Glucocorticoids

17. Structure and Function of a Transposon-Encoded CRISPR-Cas System

Halpin-Healy, Tyler Sheehan
2021
Theses
BiochemistryBiophysicsMolecular biologyVibrio choleraeRNADNA

18. The role of RNA base modification m⁶A in RNA turnover and genome dynamics in B cell programmed DNA recombination

Nair, Lekha
2021
Theses
ImmunologyMolecular biologyRNADNAMethyltransferasesMethylationGene rearrangement

19. Atf5 Links Olfactory Receptor Induced Stress Response to Proper Neuronal Function

Kahiapo, Jerome Keoki
2020
Theses
CytologyBiochemistryMolecular biologyOlfactory receptor genesSmellSensory neuronsMammals

20. Evolutionary and Functional Diversity of Regulatory Factors and Sequences that Coordinate Gene Expression

Park, Jimin
2020
Theses
Biology--ClassificationMolecular biologyMicrobiologyGenetic regulationGene expressionDNA--Synthesis