1. Discovery and Optimization of Novel Small-Molecule Inhibitors of Glutathione Peroxidase 4 Lin, Annie 2023 Theses BiologyDrug resistance in cancer cellsCell deathGlutathioneCancer cells--Effect of drugs on
2. Engineering Formate Dehydrogenase Enzymatic Activity for Non-Canonical Cofactors Through Rational Design Vainstein, Salomon 2023 Theses Chemical engineeringBiologyCytologyEnzymesComputational chemistryDehydrogenasesNAD (Coenzyme)
3. Engineering G-Protein Coupled Receptor-Based Living Yeast Diagnostics for Infectious Diseases Rios, Davida Marie 2023 Theses ChemistryBiologyCommunicable diseases--DiagnosisYeast fungi--BiotechnologyAmino acidsCandidiasis
4. Exploring a non-canonical mode of gene regulation mediated by mRNA transcript isoform switching in the context of mammalian development Keskin, Abdurrahman 2023 Theses BiologyEmbryonic stem cellsGene expressionMammals--GeneticsMammals--Development
5. Genetic Variant Effects on Transcription Factor Regulation Li, Xiaoting 2023 Theses BiologyHuman genetics--VariationDiseases--Risk factorsHuman genomeGenomicsGenetic transcriptionGene expression
6. High-throughput methods to investigate the function and pharmacological inhibition of viral proteases Hong, Seo Jung 2023 Theses VirologyBiologyCOVID-19 (Disease)Protease inhibitors
7. Identifying Critical Regulatory Elements of Alternative Splicing Recinos, Yocelyn 2023 Theses BiologyMolecular biologyGenetic engineeringRNA splicingExons (Genetics)Mammals--Genetics
8. Population genetic models of mutation rate evolution and adaptation and the impact of essential workers in the context of social distancing for epidemic control Milligan, William Robert 2023 Theses BiologyEvolution (Biology)MutagenesisGerm cellsSocial distancing (Public health)Epidemics--PreventionEpidemiologyAllelomorphismIndustrial hygiene
9. Regulation of EGFR signal transduction and cell division in quiescent Vulval Precursor Cells during dauer developmental arrest O'Keeffe, Catherine 2023 Theses BiologyDevelopmental biologyCaenorhabditis elegansStem cellsVulvaCell division
10. Rie1 and Sgn1 form an RNA-binding complex that enforces the meiotic entry cell fate decision Gaspary, Alec 2023 Theses BiologyCytologyMolecular biologyYeast--GeneticsSaccharomyces cerevisiae--Genetic aspectsRNA-protein interactionsMeiosis
11. Structural and Functional Studies of CNG channels Hu, Zhengshan 2023 Theses BiologyBiochemistryBiophysicsCyclic nucleotides--AnalysisIon channelsCryoelectronicsElectron microscopy
12. The Major Histocompatibility Complex Class I in the Pathogenesis of B-Cell Lymphomas Gomez, Karen 2023 Theses BiologyCarcinogenesisLymphomasHistocompatibilityEpstein-Barr virusCancer--Immunological aspects
13. The Role of Kinesins in Cell Fate Determination During Neurogenesis Helmer, Paige 2023 Theses BiologyKinesinNeurogeneticsNeuronsBrain--PhysiologyMammals--Nervous systemNeuroglia
14. ARP2/3- and resection-coupled genome reorganization into repair domains facilitates chromosome translocations Zagelbaum, Jennifer 2022 Theses BiologyGenomesDNA repairChromosomesPolymerizationChromatinTranslocation (Genetics)
15. Auditory Tuning in Vocal Learning Songbirds Yeh, Yow-Tyng 2022 Theses BiologyNeurosciencesSongbirdsBirds--VocalizationBirdsongsSensorimotor cortex
16. Autophagy and Hematopoietic Stem Cell Potential During Aging Dellorusso, Paul Vincent 2022 Theses BiologyGeneticsImmunologyAutophagic vacuolesHematopoietic stem cells--Therapeutic useCells--AgingGlucose--Metabolism
17. Cardiomyopathy at the Intersection of Stem Cells and Tissue Engineering Wang, Bryan Zicheng 2022 Theses BiologyMyocardium--DiseasesStem cellsGene editingTissue engineeringHeart--Diseases--Genetic aspects
18. Developing and applying novel imaging methods for human diseases Bekdash, Ramsey Azeez 2022 Theses Molecular biologyBiologyFluorescence microscopyElectrophysiologyDiagnostic imagingCOVID-19 (Disease)--TreatmentMetabolism
19. Development of genetically intact bioengineered spores of Bacillus subtilis Flores Quijano, Juan Manuel de Jesus 2022 Theses BiologyBacillus subtilis--GeneticsPlasmids--GeneticsBiotechnologyNatural pesticidesProbiotics
20. Expression and Functional Analyses of the Entire Cadherin Gene Family in C. elegans Majeed, Maryam 2022 Theses BiologyNeurosciencesCaenorhabditis elegans--GeneticsGene expressionCadherins
21. Investigating the Role of TM6SF2 in Lipid Metabolism Gibeley, Sarah B. 2022 Theses BiologyCytologyNutritionLipids--MetabolismLiver--DiseasesHyperlipidemiaGene editing
22. Investigation of Novel lincRNAs SIMALR and RP11-184M15.1 Functions in Inflammatory and Resolving Human Macrophage Cynn, Esther 2022 Theses BiologyMacrophagesApoptosisCardiovascular system--DiseasesMonocytes
23. Investigation of Novel LncRNAs Harboring Risk SNPs Associated with Celiac and Crohn's Disease Shearer, Alyssa 2022 Theses ImmunologyBiologyNon-coding RNAMacrophagesInflammation--Immunological aspects
24. Multiplexed high-throughput screening identifies broadly active rescuers of proteotoxicity Resnick, Samuel Jackson 2022 Theses BiologyAmyotrophic lateral sclerosisNervous system--DegenerationCOVID-19 (Disease)DementiaProtein folding
25. Scouring genomes and evolutionary trees for the origins of sex-biased germline mutation Wu, Felix 2022 Theses BiologyMutagenesisMammals--GeneticsBaboonsSex chromosomesCell divisionSpermatogenesis
26. Single-cell activity and network properties of dorsal raphe serotonin neurons during emotional behaviors Paquelet, Grace Elizabeth 2022 Theses NeurosciencesBiologyMammals--Nervous systemSerotoninEmotionsSerotoninergic mechanisms
27. Systems-Level Approaches to Understanding Protein Synthesis Metz, Jordan Benjamin 2022 Theses BiologyComputer scienceBioinformaticsNucleotide sequenceRibosomesProteins--Synthesis--RegulationRNA-protein interactionsAnimal models in research
28. The contribution of 14-3-3 proteins to protein aggregate homeostasis Herod, Sarah Grace 2022 Theses GeneticsBiologyAmyloidAlzheimer's disease--EtiologyParkinson's diseaseNervous system--DegenerationMeiosisRNA-protein interactions
29. The development and application of high-throughput tools for functional genomics Sheng, Jiemin 2022 Theses BiologyGenomicsNucleotide sequenceDNARNAProteins
30. The Role of Pparg in Urothelial Carinoma Xiang, Ting Wei 2022 Theses BiologyBladder--Cancer--TreatmentRosiglitazoneTretinoin
31. Towards new approaches for studying personalized gut microbiota and host-microbe interactions Huang, Yiming 2022 Theses BiologyBacteriaGastrointestinal system--MicrobiologyBacterial genetics
32. Understanding and Engineering Multicomponent Living Systems: Examples from Synthetic Genomics and Engineered Living Materials McBee, Andrew Ross MacKay 2022 Theses BiologySynthetic biologyGenomicsMetazoaAmino acidsValineMycelium
33. A Comparative Analysis of Genome Rearrangement in Ciliates Feng, Yi 2021 Theses BiologyBioinformaticsEvolution (Biology)Gene rearrangementCiliata--GeneticsEuplotesGenetic code
34. Adipocyte-specific Tribbles-1 Regulates Plasma Adiponectin and Lipoprotein Metabolism in Mice Ha, Elizabeth 2021 Theses BiologyLipoproteinsMiceCoronary heart diseaseBlood lipidsGenes
35. Broad-scale variation in human genetic diversity levels is predicted by purifying selection on coding and non-coding elements Murphy, David 2021 Theses GeneticsEvolution (Biology)BiologyHuman genomeBiodiversity
36. Computational Framework for the Identification of Neural Circuits Underlying Psychiatric Disorders Chang, Jonathan 2021 Theses NeurosciencesComputer scienceBiologyAutism spectrum disordersMutation (Biology)Basal ganglia--DiseasesLimbic system--Diseases
37. Disentangling mutation and selection in human genetic variation: promises and pitfalls Agarwal, Ipsita 2021 Theses BiologyGeneticsEvolution (Biology)Mutation (Biology)Human genomeExomes
38. Electromechanical Coupling in Cells and Its Effects on Membrane Tension and Conductance Jones Molina, John Anthony 2021 Theses BiophysicsCytologyBiologyCell membranes
39. Framework for Mapping Gene Regulation via Single-cell Genetic Screens Tan, Xiangtian 2021 Theses BiologyCytologyGenetic transcription--RegulationCancer cellsProteins--Analysis
40. Function and Regulation of ALS/FTD-associated RNA Binding Protein FUS Tsai, Yueh-Lin 2021 Theses BiologyCytologyMolecular biologyRNA-protein interactionsAmyotrophic lateral sclerosisDementia
41. Mechanisms Underlying Phenotypic Heterogeneity in Simplex Autism Spectrum Disorders Chiang, Andrew Hann 2021 Theses GeneticsBiologyBioinformaticsAutism spectrum disorders--Genetic aspectsPhenotypeMutagenesis
42. “Message in a Bottle”: Extracellular Vesicle microRNAs as Novel Biomarkers of Environmental Exposures and Health Outcomes Comfort, Nicole 2021 Theses Environmental healthBiologyEpidemiologyMicroRNAAsthma in childrenAsthma--Environmental aspectsCity childrenNucleotide sequenceSaliva--Analysis
43. Modeling Gene Therapy for Intractable Developmental and Epileptic Encephalopathy Aimiuwu, Osasumwen Virginia 2021 Theses BiologyEpilepsy--Genetic aspectsMutagenesisBrain--Diseases--TreatmentMice--GeneticsGene therapy
44. Mutagenic Repair Outcomes of DNA Double-Strand Breaks Al-Zain, Amr M. 2021 Theses BiologyMolecular biologyDouble-stranded RNACancer--EtiologyCancer--Genetic aspectsGenomesMutagenesis
45. Neural circuit control of feature tuning in CA1 during spatial learning Rolotti, Sebastian Victor 2021 Theses NeurosciencesBiologyNeurology--ResearchMemory--ResearchHippocampus (Brain)Calcium imagingElectrophysiologyOptogenetics
46. Novel Functions for Dynein Adaptor RILP in Neuronal Autophagy Khobrekar, Noopur V. 2021 Theses BiologyBiochemistryDyneinAutophagic vacuolesCell organelles
47. Regulation of heterochromatin formation by the JmjC-domain protein Epe1 Bao, Kehan 2021 Theses BiologyEukaryotic cells--GeneticsHeterochromatinChromatinDNA
48. Role of Mu-Opioid Receptors in the Behavioral Effects of the Antidepressant Tianeptine Han, Jaena 2021 Theses BiologyNeurosciencesDepression, Mental--TreatmentAntidepressantsSerotonin uptake inhibitorsMice
49. Roles of Retinoid Signaling in Urothelial Progenitor Cells Wiessner, Gregory 2021 Theses Developmental biologyBiologyEpithelium--PhysiologyBladder
50. RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulation Yuan, Qi; Dridi, Haikel; Clarke, Oliver B.; Reiken, Steven; Melville, Zephan; Wronska, Anetta; Kushnir, Alexander; Zalk, Ran; Sittenfeld, Leah; Marks, Andrew R. 2021 Articles Muscles--DiseasesCytologyBiology