251. PTEN regulates glutamine flux to pyrimidine synthesis and sensitivity to dihydroorotate dehydrogenase inhibition Mathur, Deepti 2017 Theses Pyrimidines--SynthesisFibroblastsMice--EmbryosTumorsMetabolismGlutamine--MetabolismCytologyBiologyMolecular biologyOncology
252. Regulation of Proviral Expression and Post-Translational Modifications in Embryonic Cells Lee, Andreia H. 2017 Theses BiologyVirologyCytologyGenetic regulation
253. Reliable and Elastic Propagation of Cortical Seizures In Vivo Wenzel, Michael; Hamm, Jordan P.; Peterka, Darcy; Yuste, Rafael 2017 Articles SpasmsEpilepsyNeural circuitryBiologyPicrotoxin
254. Structural and Functional Studies of TRPML1 and TRPP2 Benvin, Nicole Marie 2017 Theses BiologyBiochemistryBiophysicsTRP channelsProteins--Structure
255. Study of Short Forms of P/Q-Type Voltage-Gated Calcium Channels Feng, Qiao 2017 Theses Central nervous systemNeurotransmittersBrain--DiseasesCalcium channelsBiology
256. The Development of an Inducible Akt as a Potential Gene Therapy for Parkinson’s Disease Park, Soyeon 2017 Theses BiologyNeurosciencesParkinson's diseaseGene therapyProtein kinases
257. The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3’-end processing Aik, Wei Shen; Lin, Min-Han; Tan, Dazhi; Tripathy, Ashutosh; Marzluff, William F.; Dominski, Zbigniew; Chou, Chi-Yuan; Tong, Liang 2017 Articles Crosslinking (Polymerization)DimersCrystals--StructureBiology
258. The population genetics of human disease: The case of recessive, lethal mutations Amorim, Carlos Eduardo G.; Gao, Ziyue; Baker, Zachary; Diesel, Jose Francisco; Simons, Yuval Benjamin; Haque, Imran S.; Pickrell, Joseph K.; Przeworski, Molly F. 2017 Articles Population geneticsBiologyMutation (Biology)Medical genetics
259. The roles of Threonine-4 and Tyrosine-1 of the RNA Polymerase II C-Terminal Domain: New insights into transcription from Saccharomyces cerevisiae Yurko, Nathan Michael 2017 Theses BiologyRNA polymerasesGenetic transcriptionSaccharomyces cerevisiae
260. Transcriptional control of tumor suppressor genes in cancer Pappas, Kyrie Jean 2017 Theses AntioncogenesCancer--Genetic aspectsTumor suppressor proteinsOncologyGenetic transcription--RegulationCancerBiologyGenetics
261. Unraveling the link between the Mdm2-p53 axis and aging Wu, Danyi 2017 Theses BiologyMolecular biologyAgingp53 protein
262. Using Genomic Transgenes and the CRISPR/Cas9 Gene Editing System to Understand How Hedgehog Signaling Regulates Costal2 and Cubitus Interruptus in Drosophila melanogaster Little, Jamie 2017 Theses BiologyHedgehog proteinsMolecular biologyGenes
263. Watching the Replisome: Single-molecule Studies of Eukaryotic DNA Replication Duzdevich, Daniel 2017 Theses DNA replicationMolecular biologyCytologyEukaryotic cells--GeneticsBiologyBiophysics
264. Age is not just a number: Naive T cells increase their ability to persist in the circulation over time Rane, Sanket; Hogan, Thea; Seddon, Benedict; Yates, Andrew J. 2018 Articles BiologyT cellsAgingImmunologyHomeostasis
265. Allosteric Coupling, Nucleotide Binding and ATP Hydrolysis by Hsp70 Chaperones on a Structural Basis Wang, Wei 2018 Theses BiologyBiochemistryBiophysicsAllosteric regulationHeat shock proteins
266. An atlas of Caenorhabditis elegans chemoreceptor expression Iglesias, Berta Vidal; Aghayeva, Ulkar; Sun, Haosheng; Wang, Chen; Glenwinkel, Lori Ann; Bayer, Emily Ann; Hobert, Oliver 2018 Articles Caenorhabditis elegansChemoreceptorsNeurosciencesBiology
267. A population genetic interpretation of GWAS findings for human quantitative traits Simons, Yuval Benjamin; Bullaughey, Kevin; Hudson, Richard R.; Sella, Guy 2018 Articles GeneticsPhenotypeBiologyHuman genome
268. A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels Saponaro, Andrea; Cantini, Francesca; Porro, Alessandro; Bucchi, Annalisa; DiFrancesco, Dario; Maione, Vincenzo; Donadoni, Chiara; Introini, Bianca; Mesirca, Pietro; Mangoni, Matteo E.; Thiel, Gerhard; Banci, Lucia; Santoro, Bina; Moroni, Anna 2018 Articles BiologyCardiac pacemakersCyclic adenylic acidPeptidesMolecular biology
269. Bringing Cyclopropenium to Life Brucks, Spencer D. 2018 Theses PolymersPolyelectrolytesNanomedicineBiologyChemistry
270. Calcium imaging of the entire muscle system of Hydra reveals extensive cellular multifunctionality Szymanski, John Robert 2018 Theses BiologyNeurosciencesHydraMusclesCell physiology
271. Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons Yuan, Yuan; Xie, Shirley; Darnell, Jennifer C.; Darnell, Andrew J.; Saito, Yuhki; Phatnani, Hemali P.; Murphy, Elisabeth A.; Zhang, Chaolin; Maniatis, Tom; Darnell, Robert B. 2018 Articles Motor neuronsCytoskeletonSeptinsRNA splicingBiology
272. cis-regulatory architecture of a short-range EGFR organizing center in the Drosophila melanogaster leg Newcomb, Susan Elizabeth; Voutev, Roumen; Jory, Aurelie E.; Delker, Rebecca; Slattery, Matthew; Mann, Richard S. 2018 Articles Drosophila melanogaster--GeneticsGrowth factors--ReceptorsCloningBiologyGene expression
273. Comprehensive machine learning analysis of Hydra behavior reveals a stable basal behavioral repertoire Han, Shuting; Taralova, Ekaterina; Dupre, Christophe; Yuste, Rafael 2018 Articles NeurosciencesMachine learningAnimal behaviorBehavioral assessmentBiology
274. Context-dependent expression of a conditionally-inducible form of active Akt Park, Soyeon; Burke, Robert E.; Kareva, Tatyana; Kholodilov, Nikolai; Aime, Pascaline; Franke, Thomas F.; Levy, Oren Abraham; Greene, Lloyd A. 2018 Articles Protein kinasesDopaminergic neuronsNeurosciencesBiology
275. Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation Chua, Chee Wai; Epsi, Nusrat J.; Leung, Eva Yung; Xuan, Shouhong; Lei, Ming; Li, Bo; Bergren, Sarah; Hibshoosh, Hanina; Mitrofanova, Antonina; Shen, Michael M. 2018 Articles BiologyProstate--CancerRegenerative medicineAndrogens--ReceptorsStem cells
276. Enabling multiplexed testing of pooled donor cells through whole-genome sequencing Chan, Yingleong; Chan, Ying K.; Goodman, Daniel B.; Guo, Xiaoge; Chavez, Alejandro; Lim, Elaine T.; Church, George M. 2018 Articles Single nucleotide polymorphismsGenomesBiologyExpectation-maximization algorithms
277. Extrinsic Regulation of Hematopoietic Stem Cells in Health and Disease Decker, Matthew 2018 Theses CytologyBiologyHematopoietic stem cellsBiological control systems
278. Fatty acid synthesis and scavenging contribute to pancreatic cancer growth and maintenance Ahmed, Roshan Ara 2018 Theses PharmacologyBiologyFatty acids--SynthesisPancreas--Cancer
279. Functional odor classification through a medicinal chemistry approach Poivet, Erwan E.; Tahirova, Narmin Tahir; Peterlin, Zita; Xu, Lu; Zou, Dong-Jing; Acree, Terry; Firestein, Stuart J. 2018 Articles BiochemistryPharmaceutical chemistryOdorsBiology
280. Genomic Evolution of Glioblastoma Ladewig, Erik 2018 Theses GenomicsTumorsComputational biologyBiology
281. Hydra Behavior Dataset Han, Shuting 2018 Data (Information) HydraAnimal behaviorAnimals--FoodBiology
282. Investigating The Role Of Signaling Pathways In Adult Stem Cells Governed By Population Asymmetry Melamed, David Eric 2018 Theses BiologyCellular signal transductionAdult stem cells
283. Investigations into pathophysiologic mechanisms and treatment of primary mitochondrial diseases Siegmund, Stephanie 2018 Theses Molecular biologyMitochondrial pathologyRapamycinBiology
284. Isolation of mitochondria from Saccharomyces cerevisiae using magnetic bead affinity purification Liao, Pin-Chao; Boldogh, Istvan; Siegmund, Stephanie; Freyberg, Zachary; Pon, Liza A. 2018 Articles MitochondriaSaccharomyces cerevisiaeCell fractionationCytology--TechniqueBiology
285. Light sheet theta microscopy for rapid high-resolution imaging of large biological samples Migliori, Bianca; Datta, Malika S.; Dupre, Christophe; Apak, Mehmet C.; Asano, Shoh; Gao, Ruixuan; Boyden, Edward S.; Hermanson, Ola; Yuste, Rafael; Tomer, Raju 2018 Articles BiologyMicroscopyBrain--ImagingHigh resolution imagingNeurosciences
286. Markers and Mechanisms of β-cell Dedifferentiation Fan, Jason Chen 2018 Theses MedicineBiologyCytologyPancreatic beta cells
287. Metabolic Strategies to Cope with Overcrowding in a Pseudomonas aeruginosa Biofilm Jo, Jeanyoung 2018 Theses BiologyMicrobiologyPseudomonas aeruginosaBiofilmsMicrobial respiration
288. Multidimensional T Cell Mechanosensing Jin, Weiyang 2018 Theses Biomedical engineeringImmunologyT cellsBiologyBiomechanics
289. Multi-level analysis of regulation of EGFR signalling during Drosophila melanogaster leg proximal-distal axis patterning Newcomb, Susan Elizabeth 2018 Theses BiologyGeneticsGrowth factors--ReceptorsEpidermal growth factorDrosophila melanogaster
290. Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis Phizicky, David V.; Berchowitz, Luke E.; Bell, Stephen P. 2018 Articles Gene expressionDNA replicationMeiosisProtein kinasesBiology
291. On the Role of Sensory Cancellation and Corollary Discharge in Neural Coding and Behavior Enikolopov, Armen 2018 Theses NeurosciencesBiologySensory stimulationCochlear nucleus
292. Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites Rocamora, Frances; Zhu, Lei; Liong, Kek Yee; Dondorp, Arjen; Miotto, Olivo; Mok, Sachel Shu Li; Bozdech, Zbynek 2018 Articles ArtemisininMalaria--TreatmentDrug resistanceParasitic diseasesOxidative stressBiology
293. Parkinson’s disease-linked Parkin mutations impair glutamatergic signaling in hippocampal neurons Zhu, Mei; Cortese, Giuseppe P.; Waites, Clarissa L. 2018 Articles BiologyNeurosciencesParkinson's diseaseSynapsesMutation (Biology)
294. Pathways for kidney triglyceride accumulation Scerbo, Diego 2018 Theses BiologyBiochemistryNutritionTriglyceridesKidneys--Diseases
295. Phosphorylation dependent structural function of DNA-PKcs in DNA repair and hematopoiesis Crowe, Jennifer Lauryn 2018 Theses Molecular biologyBiologyImmunologyPhosphorylationHematopoiesisDNA repair
296. Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmission Hart, Thomas; Nguyen, Ngoc Thien Thu; Nowak, Nancy A.; Zhang, Fuming; Linhardt, Robert J.; Diuk-Wasser, Maria; Ram, Sanjay; Kraiczy, Peter; Lin, Yi-Pin 2018 Articles Lyme diseaseBorrelia burgdorferiProteinsBiology
297. Respiratory syncytial virus prolifically infects N2a neuronal cells, leading to TLR4 and nucleolin protein modulations and RSV F protein co-localization with TLR4 and nucleolin Yuan, Xiaoling; Hu, Tao; He, Hanwen; Qiu, Huan; Wu, Xuan; Chen, Jingxian; Wang, Minmin; Chen, Cheng; Huang, Shenghai 2018 Articles Respiratory syncytial virusVirus diseasesMedicineBiologyPathology
298. Simultaneous two-photon imaging and two-photon optogenetics of cortical circuits in three dimensions Yang, Weijian; Carrillo-Reid, Luis; Bando, Yuki; Peterka, Darcy; Yuste, Rafael 2018 Articles BiologyOptogeneticsNeural circuitryImaging systems in biology
299. Spatially restricted regulation of cell competition by the cytokine Spaetzle Alpar, Elif Lale 2018 Theses BiologyGeneticsCytokinesCells--Growth--Regulation
300. Structural Studies of the Integrator Complex -- pre-UsnRNA 3'-end Processing Machinery Wu, Yixuan 2018 Theses BiologyBiochemistryCatalytic RNA