1. ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function Sharma, Aarti; Lyashchenko, Alexander K.; Lu, Lei; Ebrahimi Nasrabady, Sara; Elmaleh, Margot; Mendelsohn, Monica; Nemes, Adriana; Tapia, Juan Carlos; Mentis, George Z.; Shneider, Neil 2016 Articles Nervous system--Degeneration--Molecular aspectsAmyotrophic lateral sclerosisNeurologyMedicineMolecular biologyNeurosciences
2. Genetic Pharmacotherapy as an Early CNS Drug Development Strategy: Testing Glutaminase Inhibition for Schizophrenia Treatment in Adult Mice Masson, Justine; Thomsen, Gretchen M.; Lin, Chyuan-Sheng; Merker, Robert J.; Gaisler-Salomon, Inna; Wang, Yvonne; Ernst, Rachel; Hen, Rene; Rayport, Stephen G.; Gellman, Celia; Mingote, Susana 2016 Articles Glutamic acidCentral nervous system--Effect of drugs onSchizophrenia--ChemotherapySchizophrenia--TreatmentMental healthMolecular biologyNeurosciencesMedicine
3. Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes Joseph, Leroy C.; Barca, Emanuele; Subramanyam, Prakash; Komrowski, Michael; Pajvani, Utpal B.; Colecraft, Henry M.; Hirano, Michio; Morrow, John 2016 Articles Heart cellsHeart failureObesity--Health aspectsOxidative stressMolecular biologyMedical sciencesMedicine
4. mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2 Kim, Kyeong Jin; Qiang, Li; Hayden, Matthew S.; Sparling, David P.; Purcell, Nicole H.; Pajvani, Utpal B. 2016 Articles Fatty degenerationCells--Growth--RegulationLiver--DiseasesImmunologyMedicineMolecular biology
5. TLR4 Deficiency Protects against Hepatic Fibrosis and Diethylnitrosamine-Induced Pre-Carcinogenic Liver Injury in Fibrotic Liver Weber, Susanne Nicole; Bohner, Annika; Dapito, Dianne H.; Schwabe, Robert F.; Lammert, Frank 2016 Articles Liver--CancerApoptosisLiver--FibrosisMedicineMolecular biologyOncology