1. Statistical Methods for Genetic Studies with Family History of Diseases Lee, Annie Jehe 2019 Theses BiometryStatisticsGeneticsFamilial diseasesEpidemiology
2. Diagnostic odyssey of patients with mitochondrial disease: Results of a survey Grier, Johnston; Hirano, Michio; Karaa, Amel; Shepard, Emma; Thompson, John L. 2018 Articles NeurologyGeneticsMitochondrial pathologyBiometry
3. Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations Liang, Jingjing; Le, Thu H.; Velez Edwards, Digna R.; Tayo, Bamidele O.; Gaulton, Kyle J.; Smith, Jennifer A.; Lu, Yingchang; Jensen, Richard A.; Chen, Guanjie; Yanek, Lisa R.; Schwander, Karen; Tajuddin, Salman M.; Sofer, Tamar; Kim, Wonji; Kayima, James; McKenzie, Colin A.; Fox, Ervin; Nalls, Michael A.; Young, J. Hunter; Sun, Yan V.; Lane, Jacqueline M.; Cechova, Sylvia; Zhou, Jie; Tang, Hua; Fornage, Myriam; Musani, Solomon K.; Wang, Heming; Lee, Juyoung; Adeyemo, Adebowale; Dreisbach, Albert W.; Forrester, Terrence; Chu, Pei-Lun; Cappola, Anne R.; Evans, Michele K.; Morrison, Alanna C.; Martin, Lisa W.; Wiggins, Kerri L.; Hui, Qin; Zhao, Wei; Jackson, Rebecca D.; Ware, Erin B.; Faul, Jessica D.; Reiner, Alex P.; Bray, Michael; Denny, Joshua C.; Mosley, Thomas H.; Palmas, Walter R.; Guo, Xiuqing; Papanicolaou, George J.; Penman, Alan D.; Polak, Joseph F.; Rice, Kenneth; Taylor, Ken D.; Boerwinkle, Eric; Bottinger, Erwin P.; Liu, Kiang; Risch, Neil; Hunt, Steven C.; Kooperberg, Charles; Zonderman, Alan B.; Laurie, Cathy C.; Becker, Diane M.; Cai, Jianwen; Loos, Ruth J. F.; Psaty, Bruce M.; Weir, David R.; Kardia, Sharon L. R.; Arnett, Donna K.; Won, Sungho; Edwards, Todd L.; Redline, Susan; Cooper, Richard; Rao, D. C.; Rotter, Jerome I.; Rotimi, Charles N.; Levy, Daniel; Chakravarti, Aravinda; Zhu, Xiaofeng; Franceschini, Nora 2017 Articles EpidemiologyBiometryGeneticsHypertensionAfrican Americans
4. A Simple Test of Class-Level Genetic Association Can Reveal Novel Cardiometabolic Trait Loci Qian, Jing; Nunez, Sara; Reed, Eric; Reilly, Muredach Patrick; Foulkes, Andrea S. 2016 Articles EigenvaluesGenomicsMedical geneticsMeta-analysisGeneticsBiometryMicrobiology
5. A New Estimating Equation Based Approach for Secondary Trait Analyses in Genetic Case-control Studies Song, Xiaoyu 2015 Theses BiometryGeneticsCase-control methodGeneralized estimating equations
6. A dual-clustering framework for association screening with whole genome sequencing data and longitudinal traits Lui, Ying; Huang, Chien-Hsun; Hu, Inchi; Zheng, Tian; Lo, Shaw-Hwa 2014 Articles GeneticsBiometry
7. A partition-based approach to identify gene-environment interactions in genome wide association studies Fan, Ruixue; Huang, Chien-Hsun; Hu, Inchi; Wang, Haitan; Zheng, Tian; Lo, Shaw-Hwa 2014 Articles GeneticsBiometry
8. Comparing the power of family-based association tests for sequence data with applications in the GAW18 simulated data Huang, Jing; Chen, Yong; Swartz, Michael; Ionita-Laza, Iuliana 2014 Articles Human genetics--VariationBiometryGenetics
9. Considering interactive effects in the identification of influential regions with extremely rare variants via fixed bin approach Agne, Michael; Huang, Chien-Hsun; Hu, Inchi; Wang, Haitian; Zheng, Tian; Lo, Shaw-Hwa 2014 Articles GeneticsBiometry
10. Discovering pure gene-environment interactions in blood pressure genome-wide association studies data: a two-step approach incorporating new statistics Wang, Maggie Haitan; Huang, Chien-Hsun; Zheng, Tian; Lo, Shaw-Hwa; Hu, Inchi 2014 Articles GeneticsBiometry
11. Identification of Rare Causal Variants in Sequence-Based Studies: Methods and Applications to VPS13B, a Gene Involved in Cohen Syndrome and Autism Ionita-Laza, Iuliana; Capanu, Marinela; De Rubeis, Silvia; McCallum, Kenneth; Buxbaum, Joseph D. 2014 Articles Genetic disordersHuman genetics--VariationAutismGeneticsBiometry
12. Small sample properties of rare variant analysis methods Swartz, Michael; Kim, Taebeom; Niu, Jiangong; Yu, Robert; Shete, Sanjay; Ionita-Laza, Iuliana 2014 Articles Human genetics--VariationBiometryGenetics
13. Association analysis of complex diseases using triads, parent-child dyads and singleton monads Fan, Ruzong; Lee, Annie Jehe; Lu, Zhaohui; Liu, Aiyi; Troendle, James; Mills, James 2013 Articles Medical geneticsGenetic markersFamilial diseasesAssociation schemes (Combinatorial analysis)MedicineBiometryGenetics
14. Bayesian hierarchical graph-structured model for pathway analysis using gene expression data Zhou, Hui; Zheng, Tian 2013 Articles BiometryGenetics
15. Haplotype Inference through Sequential Monte Carlo Iliadis, Alexandros 2013 Theses BiometryEngineeringGenetics
16. Maximum-parsimony haplotype frequencies inference based on a joint constrained sparse representation of pooled DNA Jajamovich, Guido H.; Iliadis, Alexandros; Anastassiou, Dimitris; Wang, Xiaodong 2013 Articles BiometryDNA--Data processingGenetics—ResearchBioinformaticsGeneticsBiology
17. Rare Variant Analysis for Family-Based Design De, Gourab; Yip, Wai-Ki; Ionita-Laza, Iuliana; Laird, Nan 2013 Articles BiometryGenetics
18. SAVI: a statistical algorithm for variant frequency identification Trifonov, Vladimir; Pasqualucci, Laura; Tiacci, Enrico; Falini, Brunangelo; Rabadan, Raul 2013 Articles Bayesian statistical decision theorySequence alignment (Bioinformatics)Gene frequency--Statistical methodsGeneticsBioinformaticsBiometry
19. Implications for health and disease in the genetic signature of the Ashkenazi Jewish population Guha, Saurav; Rosenfeld, Jeffrey; Malhotra, Anil; Gregersen, Peter; Kane, John; Pe'er, Itsik; Darvasi, Ariel; Lencz, Todd 2012 Articles GeneticsBiometry
20. APOE Genotype-Function Relationship: Evidence of −491 A/T Promoter Polymorphism Modifying Transcription Control but Not Type 2 Diabetes Risk Geng, Hua; Law, Peggy P. Y.; Ng, Maggie C. Y.; Li, Ting; Liang, Li-Yun; Ge, Tiang-Fang; Wong, Kam-Bo; Liang, Chun; Ma, Ronald C.; So, Wing-Yee; Chan, Juliana C. N.; Ho, Yuan-Yuan 2011 Articles BiometryGenetics
21. Apolipoprotein M Gene (APOM) Polymorphism Modifies Metabolic and Disease Traits in Type 2 Diabetes Zhou, Jun-Wei; Tsui, Stephen K. W.; Ng, Maggie C. Y.; Geng, Hua; Li, Sai-Kam; So, Wing-Yee; Ma, Ronald C.; Wang, Ying; Tao, Qian; Chen, Zhen-Yu; Chan, Juliana C. N.; Ho, Yuan-Yuan 2011 Articles GeneticsBiometry
22. Association screening for genes with multiple potentially rare variants: an inverse-probability weighted clustering approach Liu, Ying; Huang, Chien-Hsun; Hu, Inchi; Zheng, Tian; Lo, Shaw-Hwa 2011 Articles GeneticsBiometry
23. Identifying influential regions in extremely rare variants using a fixed-bin approach Agne, Michael; Huang, Chien-Hsun; Hu, Inchi; Wang, Haitian; Zheng, Tian; Lo, Shaw-Hwa 2011 Articles GeneticsBiometry
24. Identifying rare disease variants in the Genetic Analysis Workshop 17 simulated data: a comparison of several statistical approaches Fan, Ruixue; Huang, Chien-Hsun; Lo, Shaw-Hwa; Zheng, Tian; Ionita-Laza, Iuliana 2011 Articles GeneticsBiometry
25. Refinement of primate copy number variation hotspots identifies candidate genomic regions evolving under positive selection Lee, Charles; Johnson, Welkin; Clark, Andrew; Vallender, Eric; Babb, Paul; Iskow, Rebecca; Zhu, Qihui; Shi, Xinghua; Mills, Ryan; Ionita-Laza, Iuliana; Gokcumen, Omer 2011 Articles GeneticsBiometry
26. Analysis of genome-wide association data by large-scale Bayesian logistic regression Wang, Yuanjia; Sha, Nanshi; Fang, Yixin 2009 Articles GeneticsBiometry
27. Genome-wide gene-based analysis of rheumatoid arthritis-associated interaction with PTPN22 and HLA-DRB1 Lo, Shaw-Hwa; Chong, Lei; Xie, Jun; Huang, Chien Hsun; Qiao, Bo; Zheng, Tian 2009 Articles GeneticsBiometry
28. Rheumatoid arthritis-associated gene-gene interaction network for rheumatoid arthritis candidate genes Zheng, Tian; Qiao, Bo; Lo, Shaw-Hwa; Xie, Jun; Huang, Chien-Hsun; Cong, Lei 2009 Articles BiometryGenetics
29. Combining identity by descent and association in genetic case-control studies Zhang, Qingrun; Wang, Shuang; Ott, Jurg 2008 Articles GeneticsBiometry
30. Discovering interactions among BRCA1 and other candidate genes associated with sporadic breast cancer Lo, Shaw-Hwa; Chernoff, Herman; Cong, Lei; Ding, Yuejing; Zheng, Tian 2008 Articles BiometryGenetics
31. Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network Iossifov, Ivan; Zheng, Tian; Baron, Miron; Gilliam, T. Conrad; Rzhetsky, Andrey 2008 Articles BiometryGenetics
32. Identification of gene interactions associated with disease from gene expression data using synergy networks Watkinson, John; Wang, Xiaodong; Zheng, Tian; Anastassiou, Dimitris 2008 Articles GeneticsBiometry
33. Recessive genetic mode of an ADH4 variant in substance dependence in African-Americans: A model of utility of the HWD test Luo, Xingguang; Zuo, Lingjun; Kranzler, Henry; Wang, Shuang; Anton, Raymond; Gelernter, Joel 2008 Articles GeneticsBiometry
34. Selecting informative genes for discriminant analysis using multigene expression profiles. Yan, Xin; Zheng, Tian 2008 Articles BiometryGenetics
35. Clustering and principal-components approach based on heritability for mapping multiple gene expressions Wang, Yuanjia; Fang, Yixin; Wang, Shuang 2007 Articles PhenotypeGene expressionBiometryGenetics
36. Constructing gene association networks for rheumatoid arthritis using the backward genotype-trait association (BGTA) algorithm Ding, Yuejing; Cong, Lei; Ionita-Laza, Iuliana; Lo, Shaw-Hwa; Zheng, Tian 2007 Articles GeneticsBiometry
37. Joint study of genetic regulators for expression traits related to breast cancer Zheng, Tian; Wang, Shuang; Cong, Lei; Ding, Yuejing; Ionita-Laza, Iuliana; Lo, Shaw-Hwa 2007 Articles GeneticsBiometryBreast--Cancer--Genetic aspects
38. Pattern-based mining strategy to detect multi-locus association and gene × environment interaction Li, Zhong; Zheng, Tian; Califano, Andrea; Floratos, Aristidis 2007 Articles GeneticsBiometry
39. Transcription activity hot spot, is it real or an artifact? Wang, Shuang; Zheng, Tian; Wang, Yuanjia 2007 Articles GeneticsBiometry
40. A note on QTL detecting for censored traits Fang, Yixin 2006 Articles Censored observations (Statistics)Genetics--Mathematical modelsGeneticsBiometry
41. Backward Genotype-Trait Association (BGTA)-Based Dissection of Complex Traits in Case-Control Designs Zheng, Tian; Wang, Hui; Lo, Shaw-Hwa 2006 Articles StatisticsGeneticsBiometry
42. Generalization of DNA microarray dispersion properties: microarray equivalent of t-distribution Novak, Jaroslav; Kim, Seon-Young; Xu, Jun; Modlich, Olga; Volsky, David Julian; Honys, David; Slonczewski, Joan; Bell, Douglas; Blattner, Fred; Blumwald, Eduardo; Boerma, Marjan; Cosio, Manuel; Gatalica, Zoran; Hajduch, Marian; Hidalgo, Juan; McInnes, Roderick; Miller III, Merrill; Penkowa, Milena; Rolph, Michael; Sottosanto, Jordan; St-Arnaud, Rene; Szego, Michael; Twell, David; Wang, Charles 2006 Articles Gene expression--Mathematical modelsGene expression--Data processingBiometryDNA microarrays--Statistical methodsGenetics
43. Probing genetic overlap among complex human phenotypes Rzhetsky, Andrey; Wajngurt, David; Park, Naeun; Zheng, Tian 2006 Articles BiometryGenetics
44. A Bayesian genome screening of maximum number of drinks as an alcoholism phenotype with the new Haseman-Elston method Oh, Cheongeun; Wang, Shuang; Liu, Nianjun; Chen, Liang; Zhao, Hongyu 2005 Articles Bayesian statistical decision theory--Data processingHuman gene mappingLinkage (Genetics)Alcoholism--Genetic aspectsGeneticsBiometryMedical sciences
45. Comparison of single-nucleotide polymorphisms and microsatellites in inference of population structure Liu, Nianjun; Chen, Liang; Wang, Shuang; Oh, Cheongeun; Zhao, Hongyu 2005 Articles Microsatellites (Genetics)Human population genetics--ResearchSingle nucleotide polymorphismsBiometryGeneticsDemography
46. Construction of the model for the Genetic Analysis Workshop 14 simulated data... Greenberg, David; Zhang, Junying; Shmulewitz, Dvora; Strug, Lisa J.; Zimmerman, Regina; Singh, Veena; Marathe, Sudhir 2005 Articles Gene mappingGenetics--Data processingLinkage (Genetics)BiometryGenetics
47. PAGE: Parametric Analysis of Gene Set Enrichment Kim, Seon-Young; Volsky, David Julian 2005 Articles Bioinformatics--MethodologyStatisticsDNA microarrays--Data processingBioinformaticsGeneticsBiometry
48. Whole-genome association analysis to identify markers associated with recombination rates using single-nucleotide polymorphisms and microsatellites Huang, Song; Wang, Shuang; Liu, Nianjun; Chen, Liang; Oh, Cheongeun; Zhao, Hongyu 2005 Articles Single nucleotide polymorphismsMicrosatellites (Genetics)Gene mappingGenetic recombination--ResearchGeneticsBiometry
49. Whole-genome association studies on alcoholism comparing different phenotypes using single-nucleotide polymorphisms and microsatellites Chen, Liang; Liu, Nianjun; Wang, Shuang; Oh, Cheongeun; Carriero, Nicholas; Zhao, Hongyu 2005 Articles Microsatellites (Genetics)Alcoholism--Genetic aspectsGenetic polymorphismsGeneticsBiometryMedicine
50. Whole-genome linkage analysis in mapping alcoholism genes using single-nucleotide polymorphisms and microsatellites Wang, Shuang; Huang, Song; Liu, Nianjun; Chen, Liang; Oh, Cheongeun; Zhao, Hongyu 2005 Articles Microsatellites (Genetics)Gene mappingAlcoholism--Genetic aspectsSingle nucleotide polymorphismsBiometryBioinformaticsGenetics