1. Non-canonical WDR33 Isoforms: Characterization, Regulation, and Functional Significances in STING-Mediated Innate Immune Responses Liu, Lizhi 2023 Theses Molecular biologyImmunologyBiochemistryAmino acid sequenceGene expressionMessenger RNAOligomerizationInterferon
2. Small molecules modulating ferroptosis in disease models Tan, Hui 2023 Theses BiochemistryCell deathCancer--TreatmentDiseases--EtiologyHuntington's diseaseLymphomasKidneys--DiseasesNervous system--Diseases
3. Structural and Functional Studies of CNG channels Hu, Zhengshan 2023 Theses BiologyBiochemistryBiophysicsCyclic nucleotides--AnalysisIon channelsCryoelectronicsElectron microscopy
4. Structure and Function of Glutamate Receptor-Like Channels (GLRs) Green, Marriah Noel 2023 Theses NutritionBiochemistryBiophysicsGlutamic acidLigand binding (Biochemistry)Arabidopsis thalianaCell receptors
5. Structure and Neutralization of Viral Fusion Proteins Casner, Ryan Gavin 2023 Theses BiochemistryCOVID-19 (Disease)ImmunoglobulinsCryoelectronicsVaccines--Design
6. The role of ER-mitochondria contact sites in the regulation of glucose metabolism: a tale of two mitochondria and its relevance to amyotrophic lateral sclerosis Tamucci, Kirstin Arianna 2023 Theses BiochemistryMolecular biologyNutritionGlucose--MetabolismMitochondriaMitochondrial membranesEndoplasmic reticulumMotor neuronsAmyotrophic lateral sclerosis
7. Lipids on Fire: Identifying and Targeting Subcellular Membranes that Drive Ferroptosis Von Krusenstiern, Alfred Nikolai 2022 Theses BiochemistryCell deathLipids--PeroxidationCancer--TreatmentEndoplasmic reticulumFatty acidsRaman effectConfocal fluorescence microscopy
8. Molecular Insights into Ferroptosis as a Therapeutic Target for Huntington’s Disease Daniels, Jacob D. 2022 Theses PharmacologyBiochemistryHuntington's disease--TreatmentCell deathProbucol
9. Structural studies on bestrophin anion channels by cryogenic electron microscopy Owji, Aaron Paul 2022 Theses BiophysicsBiochemistryEye--PhysiologyChloride channelsKlebsiella pneumoniaeMammalsMutagenesis
10. The Role of Chromatin in Olfaction Kodra, Albana Lavinia 2022 Theses ChromatinOlfactory receptor genesCOVID-19 (Disease)--Psychological aspectsGeneticsMolecular biologyBiochemistryEpithelium
11. A p53-independent role for MDM2-MDMX in cell cycle progression Klein, Alyssa Michelle 2021 Theses CytologyMolecular biologyBiochemistryCancerMutation
12. Directed Evolution of Protein Receptor Binding for Small Molecule Therapeutics Using Fluorescence Polarization Bannier, Sean David 2021 Theses ChemistryBiochemistryBiophysicsTetracylcinesProtein bindingPolarization (Light)Yeast
13. Discovery of Novel Ferroptosis Regulators Using Genetic and Lipidomic Analyses Bezjian, Carla Tara 2021 Theses CytologyMolecular biologyBiochemistryCell deathGenetic regulationPhospholipids
14. How to steal ribosomes: structural studies of two different internal ribosome entry sites Neupane, Ritam 2021 Theses BiochemistryBiophysicsVirologyRibosomesEukaryotic cells
15. Novel Functions for Dynein Adaptor RILP in Neuronal Autophagy Khobrekar, Noopur V. 2021 Theses BiologyBiochemistryDyneinAutophagic vacuolesCell organelles
16. Structural and Biochemical Studies of the Human pre-mRNA 3’-end Processing Complex Hamilton, Keith 2021 Theses BiochemistryBiophysicsMessenger RNA--AnalysisMutagenesis
17. Structural and functional characterization of the retinol-binding protein receptor STRA6 Costabile, Brianna Kay 2021 Theses BiochemistryEpitheliumVitamin A deficiencyVitamin APlacentaChoroid plexusElectron microscopyCalmodulin--Physiological effectZebra danio
18. Structure and Function of a Transposon-Encoded CRISPR-Cas System Halpin-Healy, Tyler Sheehan 2021 Theses BiochemistryBiophysicsMolecular biologyVibrio choleraeRNADNA
19. Visualizing cell surface interactions using cryogenic electron microscopy Rapp, Micah 2021 Theses BiophysicsBiochemistryElectron microscopyCOVID-19 (Disease)Low temperature engineeringCell membranesCell receptorsImmunoglobulins
20. Atf5 Links Olfactory Receptor Induced Stress Response to Proper Neuronal Function Kahiapo, Jerome Keoki 2020 Theses CytologyBiochemistryMolecular biologyOlfactory receptor genesSmellSensory neuronsMammals
21. Expanding Silane-Mediated Coupling Methodologies for the Formation of Medicinally Relevant Structural Motifs Hughes, Isaac 2020 Theses Chemistry, OrganicBiochemistrySilane compounds
22. Investigation of Ribonuclease HI handle region dynamics using Solution-state nuclear magnetic resonance spectroscopy, Molecular Dynamic simulations and X-ray crystallography Martin, James Arthur 2020 Theses BiophysicsBiochemistryHIV (Viruses)Mouse leukemia virusesRNAEndonucleasesNuclear magnetic resonance spectroscopy
23. Structural and Biophysical Studies of Hair Cell Mechanotransduction Proteins Dionne, Gilman 2020 Theses BiochemistryBiophysicsProteinsCellular signal transduction--Research
24. The Critical Assessment of Protein Dynamics using Molecular Dynamics (MD) Simulations and Nuclear Magnetic Resonance (NMR) Spectroscopy Experimentation Hsu, Andrew 2020 Theses BiophysicsBiochemistryNuclear magnetic resonance spectroscopyMolecular dynamics--Computer simulation
25. The Regulation of Mitochondrial Complex I Biogenesis in Drosophila Flight Muscles Garcia, Christian Joel 2020 Theses PhysiologyBiochemistryDrosophila melanogasterMitochondriaMitochondria--Formation
26. Biomolecular NMR spectroscopy: Application to the study of the piRNA-pathway protein GTSF1, and backbone and side-chain spin relaxation methods development O'Brien, Paul 2019 Theses BiophysicsBiochemistryNuclear magnetic resonance spectroscopyProteins--StructureMolecular dynamics
27. Genetic Mechanisms of Regulated Stochastic Gene Expression Horta, Adan 2019 Theses NeurosciencesBiochemistryGeneticsOlfactory receptor genesGene expressionCadherinsHuman genetics--Variation
28. Liver X Receptor cis-Repression and Cholesterol Efflux Restrain Innate Immunity and Coronary Artery Disease Thomas, David George 2019 Theses CytologyMolecular biologyBiochemistryAtherosclerosis--PreventionImmunityNuclear receptors (Biochemistry)
29. Mechanisms and therapeutic targeting of NT5C2 mutations in relapsed acute lymphoblastic leukemia Dieck, Chelsea 2019 Theses BiochemistryLymphoblastic leukemiaDrug resistanceOncologyMutation (Biology)Molecular biology
30. Molecular Approaches to Targeting Oncogenic KRAS and Ferroptosis Feng, Huizhong 2019 Theses Molecular biologyBiochemistryCytologyBiochemical markersCancerCell death
31. Novel functions of C9ORF72, a gene involved in ALS/FTD Fomin, Vitalay 2019 Theses BiologyBiochemistryGeneticsCytologyAmyotrophic lateral sclerosisFrontotemporal dementiaGene expression
32. Nucleosome Curtains and their application to the study of DNA condensation by condensin Moevus, Corentin Jean 2019 Theses BiochemistryBiophysicsDNACondensed matter
33. Solving Challenging Structures using Single-Particle Cryogenic Electron Microscopy Tan, Yong Zi 2019 Theses BiochemistryBiophysicsElectron microscopyMacromolecules--StructureRibosomesMembrane proteinsCytology--Technique
34. Structural Analyses of the Transient Receptor Potential Channels TRPV3 and TRPV6 McGoldrick, Luke Lawrence Reedy 2019 Theses BiochemistryMolecular biologyTRP channelsStructure-activity relationships (Biochemistry)Ion channels
35. Structural Investigation of Plasmodium falciparum Chloroquine Resistance Transporter in the Context of Anti-Malarial Drug Resistance Kim, Jonathan Young 2019 Theses BiochemistryMalariaDrug resistanceAntimalarialsDrugs--Physiological transport
36. Structural studies of the yeast transcription termination complex Nrd1-Nab3-Sen1 Zhang, Yinglu 2019 Theses BiologyMolecular biologyBiochemistryRNA polymerasesGenetic transcription
37. The Mechanism of NusG-Mediated Transcription-Translation Coupling and The Role of RacR in Transcription Regulation in Escherichia coli Bailey, Elizabeth Jean 2019 Theses BiochemistryMolecular biologyChemistryGenetic transcription--RegulationEscherichia coli
38. Using single molecule magnetic tweezers to dissect titin energy release during muscle contraction Eckels, Edward Charles 2019 Theses BiophysicsBiochemistryPhysiologyMagnetic tweezersMuscle contractionProtein folding
39. Allosteric Coupling, Nucleotide Binding and ATP Hydrolysis by Hsp70 Chaperones on a Structural Basis Wang, Wei 2018 Theses BiologyBiochemistryBiophysicsAllosteric regulationHeat shock proteins
40. Characterization of a novel Ser/Thr kinase/phosphatase pair in Escherichia coli Rajagopalan, Krithika 2018 Theses MicrobiologyBiochemistryPhosphatasesProtein kinasesEscherichia coliSerine
41. Characterization of the human homozygous R182W POLG2 mutation in mitochondrial DNA depletion syndrome Hoff, Kirsten E.; DeBalsi, Karen L.; Sanchez Quintero, Maria Jose; Longley, Matthew J.; Hirano, Michio; Naini, Ali B.; Copeland, William C. 2018 Articles Mitochondrial DNAMutation (Biology)CytologyBiochemistryFibroblasts
42. Crk proteins transduce FGF signaling to promote lens fiber cell elongation Collins, Tamica; Mao, Yingyu; Li, Hongge; Bouaziz, Michael; Hong, Angela; Feng, Gen-Sheng; Wang, Fen; Quilliam, Lawrence A.; Chen, Lin; Park, Taeju; Curran, Tom; Zhang, Xin 2018 Articles Fibroblast growth factorsBiochemistryDevelopmental biologyCells--Morphology
43. Design and Synthesis of 3'-Oxygen-Modified Cleavable Nucleotide Reversible Terminators for Scarless DNA Sequencing by Synthesis Hsieh, Min-Kang 2018 Theses Chemical engineeringBiochemistryBiomedical engineeringNucleotide sequence
44. Development of Single Molecule Electronic SNP Assays using Polymer Tagged Nucleotides and Nanopore Detection Cho, Youngjin 2018 Theses BiochemistryBiomedical engineeringNanoporesSingle nucleotide polymorphisms
45. Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES Pisareva, Vera P.; Pisarev, Andrey V.; Fernández, Israel S. 2018 Articles VirologyRNAHepatitis C virusBiochemistry
46. Dynamic Nuclear Polarization with Biradical Affinity Reagents Rogawski, Rivkah 2018 Theses BiophysicsChemistryBiochemistryPolarization (Nuclear physics)Biradicals
47. Functional odor classification through a medicinal chemistry approach Poivet, Erwan E.; Tahirova, Narmin Tahir; Peterlin, Zita; Xu, Lu; Zou, Dong-Jing; Acree, Terry; Firestein, Stuart J. 2018 Articles BiochemistryPharmaceutical chemistryOdorsBiology
48. Integration of EGFR and LIN-12/Notch signaling in Vulval Precursor Cell fate specification in Caenorhabditis elegans Underwood, Ryan 2018 Theses BiochemistryMetazoaCell interactionCellular signal transductionBiophysics
49. Pathways for kidney triglyceride accumulation Scerbo, Diego 2018 Theses BiologyBiochemistryNutritionTriglyceridesKidneys--Diseases
50. Resonance-energy-transfer-based fluorescence imaging and free energy perturbation calculation Xu, Fang 2018 Theses Chemistry, Physical and theoreticalProtein-protein interactionsFluorescenceEnergy transferBiochemistry