1. Mammalian translation termination intermediates captured using PDMS microfluidics-based time-resolved cryo-EM (TRCEM) Dadhwal, Prikshat 2024 Theses BiologyBiochemistryBiophysicsEukaryotic cells--GeneticsGenetic translationRibosomesSilicaCryoelectronics
2. Structural and Functional Studies of CNG channels Hu, Zhengshan 2023 Theses BiologyBiochemistryBiophysicsCyclic nucleotides--AnalysisIon channelsCryoelectronicsElectron microscopy
3. Structure and Function of Glutamate Receptor-Like Channels (GLRs) Green, Marriah Noel 2023 Theses NutritionBiochemistryBiophysicsGlutamic acidLigand binding (Biochemistry)Arabidopsis thalianaCell receptors
4. Structural studies on bestrophin anion channels by cryogenic electron microscopy Owji, Aaron Paul 2022 Theses BiophysicsBiochemistryEye--PhysiologyChloride channelsKlebsiella pneumoniaeMammalsMutagenesis
5. Directed Evolution of Protein Receptor Binding for Small Molecule Therapeutics Using Fluorescence Polarization Bannier, Sean David 2021 Theses ChemistryBiochemistryBiophysicsTetracylcinesProtein bindingPolarization (Light)Yeast
6. How to steal ribosomes: structural studies of two different internal ribosome entry sites Neupane, Ritam 2021 Theses BiochemistryBiophysicsVirologyRibosomesEukaryotic cells
7. Structural and Biochemical Studies of the Human pre-mRNA 3’-end Processing Complex Hamilton, Keith 2021 Theses BiochemistryBiophysicsMessenger RNA--AnalysisMutagenesis
8. Structure and Function of a Transposon-Encoded CRISPR-Cas System Halpin-Healy, Tyler Sheehan 2021 Theses BiochemistryBiophysicsMolecular biologyVibrio choleraeRNADNA
9. Visualizing cell surface interactions using cryogenic electron microscopy Rapp, Micah 2021 Theses BiophysicsBiochemistryElectron microscopyCOVID-19 (Disease)Low temperature engineeringCell membranesCell receptorsImmunoglobulins
10. Investigation of Ribonuclease HI handle region dynamics using Solution-state nuclear magnetic resonance spectroscopy, Molecular Dynamic simulations and X-ray crystallography Martin, James Arthur 2020 Theses BiophysicsBiochemistryHIV (Viruses)Mouse leukemia virusesRNAEndonucleasesNuclear magnetic resonance spectroscopy
11. Structural and Biophysical Studies of Hair Cell Mechanotransduction Proteins Dionne, Gilman 2020 Theses BiochemistryBiophysicsHair cellsProteinsCellular signal transduction--Research
12. The Critical Assessment of Protein Dynamics using Molecular Dynamics (MD) Simulations and Nuclear Magnetic Resonance (NMR) Spectroscopy Experimentation Hsu, Andrew 2020 Theses BiophysicsBiochemistryNuclear magnetic resonance spectroscopyMolecular dynamics--Computer simulation
13. Biomolecular NMR spectroscopy: Application to the study of the piRNA-pathway protein GTSF1, and backbone and side-chain spin relaxation methods development O'Brien, Paul 2019 Theses BiophysicsBiochemistryNuclear magnetic resonance spectroscopyProteins--StructureMolecular dynamics
14. Nucleosome Curtains and their application to the study of DNA condensation by condensin Moevus, Corentin Jean 2019 Theses BiochemistryBiophysicsDNACondensed matter
15. Solving Challenging Structures using Single-Particle Cryogenic Electron Microscopy Tan, Yong Zi 2019 Theses BiochemistryBiophysicsElectron microscopyMacromolecules--StructureRibosomesMembrane proteinsCytology--Technique
16. Using single molecule magnetic tweezers to dissect titin energy release during muscle contraction Eckels, Edward Charles 2019 Theses BiophysicsBiochemistryPhysiologyMagnetic tweezersMuscle contractionProtein folding
17. Allosteric Coupling, Nucleotide Binding and ATP Hydrolysis by Hsp70 Chaperones on a Structural Basis Wang, Wei 2018 Theses BiologyBiochemistryBiophysicsAllosteric regulationHeat shock proteins
18. Dynamic Nuclear Polarization with Biradical Affinity Reagents Rogawski, Rivkah 2018 Theses BiophysicsChemistryBiochemistryPolarization (Nuclear physics)Biradicals
19. Integration of EGFR and LIN-12/Notch signaling in Vulval Precursor Cell fate specification in Caenorhabditis elegans Underwood, Ryan 2018 Theses BiochemistryMetazoaCell interactionCellular signal transductionBiophysics
20. RNA force field with accuracy comparable to state-of-the-art protein force fields Tan, Dazhi; Piana, Stefano; Dirks, Robert M.; Shaw, David Elliot 2018 Articles BiochemistryBiophysicsRNA-protein interactionsMolecular dynamicsNucleic acids
21. Routine single particle CryoEM sample and grid characterization by tomography Noble, Alex J.; Dandey, Venkata P.; Wei, Hui; Brasch, Julia; Chase, Jillian; Acharya, Priyamvada; Tan, Yong Zi; Zhang, Zhening; Kim, Laura Y.; Scapin, Giovanna; Rapp, Micah Allen; Eng, Edward T.; Rice, William J.; Cheng, Anchi; Negro, Carl J.; Shapiro, Lawrence S.; Kwong, Peter D.; Jeruzalmi, David; des Georges, Amedee; Potter, Clinton; Carragher, Bridget 2018 Articles TomographyBiochemistryParticlesBiophysicsElectron microscopy
22. Structural and biophysical studies of the Drosophila melanogaster Dpr and DIP families Cosmanescu, Filip 2018 Theses BiochemistryNeurosciencesBiophysicsDrosophila melanogasterNeurons
23. Systematically Mapping the Epigenetic Context Dependence of Transcription Factor Binding Kribelbauer, Judith Franziska 2018 Theses BiochemistryBioinformaticsBiophysicsTranscription factorsGene regulatory networksEpigenetics
24. The Role of Eukaryotic Recombinase Loop L1 During Homologous Recombination Steinfeld, Justin Benjamin 2018 Theses BiophysicsBiochemistryGeneticsGenetic recombinationEukaryotic cells
25. The Saccharomyces cerevisiae Srs2 Helicase Regulates Homologous Recombination through the Disassembly of Recombination Intermediates Kaniecki, Kyle Stephen 2018 Theses GeneticsBiophysicsBiochemistrySaccharomyces cerevisiaeGenetic recombination
26. Cryo-electron microscopy and single particle reconstructions of the Leishmania major ribosome and of the encephalomyocarditis virus internal ribosome entry site bound to the 40S subunit Jobe, Amy Beth 2017 Theses Electron microscopyRibosomesLeishmaniaRNACryoelectronicsBiologyBiochemistryBiophysics
27. Nanoscale Electrical and Coarse-grained Molecular Dynamics Studies of Influenza Hemagglutinin-mediated Membrane Fusion Pores Alcott, Brett Eugene 2017 Theses BiophysicsBiochemistryVirologyMolecular dynamicsMembrane fusion
28. Regulation of Release Factor 2 in Non-canonical Translation Pathways Huang, Bridget Yih Jiin 2017 Theses Bacterial proteinsRibosomesBiochemistryProteins--SynthesisBiophysics
29. Single-molecule observations of hRPA, RAD51, and RAD52 on single-stranded DNA Ma, Chu Jian 2017 Theses BiochemistryBiophysicsDNA replicationGenetic recombinationMolecular biology
30. Structural and Functional Studies of TRPML1 and TRPP2 Benvin, Nicole Marie 2017 Theses BiologyBiochemistryBiophysicsTRP channelsProteins--Structure
31. Cryo-electron microscopy studies of dynamical features of ribosomes during the translation process Sun, Ming 2016 Theses BiophysicsProteins--StructureRibosomes--StructureRibosomesCryoelectronicsBiologyBiochemistry
32. Oxidative Folding in Bacteria: Studies Using Single Molecule Force Spectroscopy Kahn, Thomas 2016 Theses Protein foldingOxidoreductasesEscherichia coli--PhysiologyOxidationBiophysicsBiochemistry
33. Understanding complex biomolecular systems through the synergy of molecular dynamics simulations, NMR spectroscopy and X-Ray crystallography Zeiske, Tim 2016 Theses Molecular dynamics--Simulation methodsMolecular dynamics--Computer simulationNuclear magnetic resonance spectroscopyBiomolecules--Computer simulationX-ray crystallographyMacromolecules--StructureMolecular dynamicsBiophysicsBiochemistry
34. Identification and Biophysical Characterization of Small Molecules Modulating Protein Disulfide Isomerase in Neurodegenerative Diseases Kaplan, Anna 2015 Theses Nervous system--DegenerationNeuroprotective agentsProtein disulfide isomeraseBiophysicsBiochemistryBiology
35. Protein Structure Dynamics and Function at Micelle and Particle Interfaces Chin, Michael 2015 Theses ChemistryBiochemistryBiophysics
36. Winning the cellular lottery: how proteins reach and recognize targets in DNA Redding, Sy Eugene 2015 Theses Promoters (Genetics)DNA-protein interactionsDNA-binding proteinsBiophysicsBiochemistryBiology
37. Learning from cadherin structures and sequences: affinity determinants and protein architecture Felsovalyi, Klara 2014 Theses Protein bindingCadherinsBiochemistryBioinformaticsBiophysics
38. Structural and biophysical characterization of protocadherin extracellular regions Wolcott, Holly Noelle 2014 Theses BiochemistryBiophysics
39. CysZ: Structural and Functional Studies of a Novel Sulfate Transport Protein Assur, Zahra 2013 Theses CytologyCarrier proteinsBiochemistryBiophysics
40. Orientations and Proximities of the Extracellular Ends of Transmembrane Helices S0 and S4 in Open and Closed BK Potassium Channels Niu, Xiaowei; Liu, Guoxia; Wu, Roland; Chudasama, Neelesh; Zakharov, Sergey; Karlin, Arthur; Marx, Steven O. 2013 Articles BiochemistryMolecular biologyBiophysicsMedicine
41. Quantification of gait parameters in freely walking wild type and sensory deprived Drosophila melanogaster Mendes, Cesar; Bartos, Imre; Akay, Turgay; Marka, Szabolcs; Mann, Richard S. 2013 Articles BiochemistryBiophysicsNeurosciences
42. Structural and Functional Studies of Biotin-Dependent Carboxylases Huang, Christine S. 2013 Theses BiochemistryBiophysics
43. An Analysis of the Essential Chromatin Factor Zinc Finger Protein 1 (ZFP-1), and a Study of the Involvement of RNAi factors in Histone Processing in Caenorabditis Elegans Anastasiades Avgousti, Daphne Christina 2012 Theses BiochemistryBiophysicsCaenorhabditis elegansChromatinHistonesRNANucleosomes
44. Developmental Regulation of Chromatin Conformation by Hox Proteins in Drosophila Angelopoulos, Marios; McKay, Daniel J.; Mann, Richard S. 2012 Articles BiochemistryBiophysics
45. Mechanochemical Methods for Single Molecule Biochemistry and Studies of Thiol-Disulfide Exchange in Proteins Kosuri, Pallav 2012 Theses BiophysicsBiochemistryBiology
46. Single-Molecule Analysis of Ribosome and Initiation Factor Dynamics during the Late Stages of Translation Initiation MacDougall, Daniel David 2012 Theses Genetic translationBiochemistryRibosomesBiophysics
47. The Catalytic Efficiency and Conformational Dynamics of Escherichia coli DNA Repair Enzyme AlkB Ergel, Burce 2012 Theses BiochemistryBiophysicsOxidoreductasesCatalysisProteins
48. Gates and Latches: the mechanochemistry of ATP binding in kinesin 1 and Eg5 Behnke-Parks, William M. 2011 Theses BiologyBiophysicsBiochemistryKinesinMechanical chemistryCell division
49. Ligand-Protein Interactions in Cytochromes Catalano, Jaclyn 2011 Theses ChemistryBiochemistryBiophysics
50. The Role of Initiation Factor Dynamics in Translation Initiation Elvekrog, Margaret Mary 2011 Theses ChemistryBiophysicsBiochemistry
51. Visualizing the One-Dimensional Diffusion of DNA Mismatch Repair Proteins at the Single-Molecule Level Gorman, Jason 2011 Theses BiologyBiochemistryBiophysicsDNA repairEukaryotic cells--Genetics
52. Minimum energy conformations of DNA dimeric subunits: Potential energy calculations for dGpdC, dApdA, dCpdC, dGpdG, and dTpdT Broyde, Suse B.; Wartell, Roger M.; Stellman, Steven D.; Hingerty, B. 1978 Articles BiochemistryBiophysicsGenetics
53. Influence of ribose 2′-O-methylation on GpC conformation by classical potential energy calculations Stellman, Steven D.; Broyde, Suse B.; Wartell, Roger M. 1976 Articles BiochemistryBiophysicsGenetics
54. Classical potential energy calculations for ApA, CpC, GpG, and UpU. The influence of the bases on RNA subunit conformations Broyde, Suse B.; Wartell, Roger M.; Stellman, Steven D.; Hingerty, Brian; Landridge, Robert 1975 Articles BiochemistryBiophysicsGenetics
55. Conformation of a rare nucleoside in the anti-codon loop of tRNAs: Potential energy calculations for 2′-O-methyl cytidine Stellman, Steven D.; Hingerty, B.; Broyde, Suse B.; Langridge, R. 1975 Articles BiochemistryBiophysicsGenetics
56. Structure of guanylyl-3′,5′-cytidine monophosphate. II. Description of the molecular and crystal structure of the calcium derivative in space group P2₁ Hingerty, B.; Subramanian, E.; Stellman, Steven D.; Broyde, Suse B.; Sato, T.; Langridge, R. 1975 Articles BiochemistryBiophysicsGenetics
57. The A and B conformations of DNA and RNA subunits. Potential energy calculations for dGpdC Broyde, Suse B.; Stellman, Steven D.; Wartell, Roger M. 1975 Articles BiochemistryBiophysicsGenetics
58. Conformational stability in dinucleoside phosphate crystals. Semiempirical potential energy calculations for uridylyl-3'-5'-adenosine monophosphate (UpA) and guanylyl-3',5'-cytidine monophosphate (GpC) Broyde, Suse B.; Stellman, Steven D.; Hingerty, B.; Langridge, R. 1974 Articles BiochemistryBiophysicsGenetics