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1. Generating Reliable and Responsive Observational Evidence: Reducing Pre-analysis Bias

Ostropolets, Anna
2023
Theses
BioinformaticsDecision makingPhenotype

2. The itaconate-driven immunometabolic response to S. aureus promotes persistent lung infection

Tomlinson, Kira Leigh
2023
Theses
MicrobiologyImmunologyBioinformaticsStaphylococcus aureus infectionsBiofilmsGlycolysisPneumoniaNeutrophils--Immunology

3. Common and rare genetic effects on the transcriptome and their contribution to human traits

Einson, Jonah
2022
Theses
BioinformaticsHuman genetics--VariationBiology--ClassificationHuman genomeGenetic regulation

4. Mind the developmental gap: Identifying adverse drug effects across childhood to evaluate biological mechanisms from growth and development

Giangreco, Nicholas Paul
2022
Theses
BioinformaticsDevelopmental biologyChild developmentDrugs--Safety measuresDrugs--ToxicologyMedical statistics

5. Myeloid Heterogeneity in the Hippocampus

Chintamen, Sana
2022
Theses
NeurosciencesImmunologyBioinformaticsHippocampus (Brain)Developmental neurobiologyMice as laboratory animalsMacrophages--ResearchMicroglia

6. Systems-Level Approaches to Understanding Protein Synthesis

Metz, Jordan Benjamin
2022
Theses
BiologyComputer scienceBioinformaticsNucleotide sequenceRibosomesProteins--Synthesis--RegulationRNA-protein interactionsAnimal models in research

7. A Comparative Analysis of Genome Rearrangement in Ciliates

Feng, Yi
2021
Theses
BiologyBioinformaticsEvolution (Biology)Gene rearrangementCiliata--GeneticsEuplotesGenetic code

8. Characterizing molecular drivers of clinical outcome in pediatric acute leukemias by systems biology and machine learning

Alloy, Alexandre Paul
2021
Theses
BioinformaticsLeukemia--Genetic aspectsLeukemia in childrenMachine learningAcute leukemia

9. Genetic regulatory variant effects across tissues and individuals

Flynn, Elise Duboscq
2021
Theses
BioinformaticsMedical geneticsGene expression--ResearchHuman genomeCoronary heart disease--Genetic aspectsCoronary arteriesPhenotype

10. Integration of Functional Genomic Data in Genetic Analysis

Chen, Siying
2021
Theses
BioinformaticsMedical genetics--ResearchHuman genomeEpigeneticsAutism spectrum disorders--Genetic aspects

11. Mechanisms Underlying Phenotypic Heterogeneity in Simplex Autism Spectrum Disorders

Chiang, Andrew Hann
2021
Theses
GeneticsBiologyBioinformaticsAutism spectrum disorders--Genetic aspectsPhenotypeMutagenesis

12. Metabolic evaluation of genetic and environmental contributors to Alzheimer’s disease

Kalia, Vrinda
2021
Theses
Environmental healthBioinformaticsToxicologyAlzheimer's disease--Genetic aspectsCaenorhabditis elegansAfrican AmericansCaribbean AmericansWhite people

13. Methods for modeling the dynamics of microbial communities

Joseph, Tyler
2021
Theses
BioinformaticsNucleotide sequenceMicrobiologyBiotic communitiesIrritable colon

14. Post-transcriptional gene expression regulation in developmental disorders

Kitaygorodsky, Alexander
2021
Theses
BioinformaticsGeneticsComputer scienceGene expressionGenomesNeural networks (Neurobiology)

15. Towards unified medical evidence computation from literature for evidence-based medicine

Kang, Tian
2021
Theses
BioinformaticsMedical care--Mathematical modelsMedicine

16. Computational Analysis of Biomolecular Data for Medical Applications from Bulk to Single-cell

Zhu, Kaiyi
2020
Theses
Electrical engineeringBioinformaticsNucleotide sequenceDNARNABiomolecules--AnalysisMolecular diagnosis

17. Electronic Health Record-Derived Phenotyping Models to Improve Genomic Research in Stroke

Thangaraj, Phyllis Mary
2020
Theses
BioinformaticsGeneticsCerebrovascular diseaseCerebrovascular disease--Risk factorsMedical records--Data processingMachine learning--Industrial applications

18. Generative Models for Synthetic Biology

Blazejewski, Tomasz
2020
Theses
BioinformaticsBiology--ClassificationMolecular biologySynthetic biologyMachine learningAmino acid sequence

19. Loop Prediction and Homology Modeling with High Resolution

Xu, Tianchuan
2020
Theses
BioinformaticsProteins--Structure--Computer simulationHomology (Biology)Sequence alignment (Bioinformatics)

20. Mosaicism and the genetic architecture of congenital heart disease

Hsieh, Alexander Lin
2020
Theses
BioinformaticsGeneticsCongenital heart diseaseMosaicismDiseases--Causes and theories of causation