1. Allosteric Coupling, Nucleotide Binding and ATP Hydrolysis by Hsp70 Chaperones on a Structural Basis Wang, Wei 2018 Theses BiologyBiochemistryBiophysicsAllosteric regulationHeat shock proteins
2. Altered lipid metabolism in persister cells drives ferroptosis sensitivity Reznik, Eduard 2024 Theses CytologyBiochemistryCell deathCancer cells--Effect of drugs onCancer--ChemotherapyBiochemical markers
3. An Analysis of the Essential Chromatin Factor Zinc Finger Protein 1 (ZFP-1), and a Study of the Involvement of RNAi factors in Histone Processing in Caenorabditis Elegans Anastasiades Avgousti, Daphne Christina 2012 Theses BiochemistryBiophysicsCaenorhabditis elegansChromatinHistonesRNANucleosomes
4. A p53-independent role for MDM2-MDMX in cell cycle progression Klein, Alyssa Michelle 2021 Theses CytologyMolecular biologyBiochemistryCancerMutation
5. Application and development of methods towards the target identification of biologically-active small molecules SriRamaratnam, Rohitha 2011 Theses ChemistryBiologyMoleculesBiochemistryBiochemical geneticsGene targeting
6. Artificial Metabolons: Design of Self-Assembled Bio-Complexes Garcia, Kristen E. 2017 Theses Chemical engineeringProteinsBiochemistry
7. Atf5 Links Olfactory Receptor Induced Stress Response to Proper Neuronal Function Kahiapo, Jerome Keoki 2020 Theses CytologyBiochemistryMolecular biologyOlfactory receptor genesSmellSensory neuronsMammals
8. Biochemical and Genetic Investigation of Immature Murine Leukemia Virus Assembly Tinaztepe, Sedef 2017 Theses VirologyBiochemistryCytologyMouse leukemia virusesCytoskeletal proteinsRetroviruses
9. Biology of maintenance and de novo methylation mediated by DNA methyltransferase-1 Yarychkivska, Olga 2017 Theses DNA--MethylationMethyltransferasesDNA replicationCell divisionGenomicsGeneticsBiochemistryBiology
10. Biomolecular NMR spectroscopy: Application to the study of the piRNA-pathway protein GTSF1, and backbone and side-chain spin relaxation methods development O'Brien, Paul 2019 Theses BiophysicsBiochemistryNuclear magnetic resonance spectroscopyProteins--StructureMolecular dynamics
11. Building a Genetic System in Yeast to Search for High Affinity Proteins in Sequence Space Merguerian, Matthew Douglas 2013 Theses Molecular biologyBiochemistryCytologyProtein bindingYeast--GeneticsProtein engineering
12. Characterization of a novel Ser/Thr kinase/phosphatase pair in Escherichia coli Rajagopalan, Krithika 2018 Theses MicrobiologyBiochemistryPhosphatasesProtein kinasesEscherichia coliSerine
13. Characterizing the Interaction of the ATP Binding Cassette Transporters (G subfamily) with the Intracellular Protein Lipid Environment Gulati, Sonia 2011 Theses BiochemistryMedical sciences
14. Chloride Intracellular Channels 1 and 4 function in distinct branches of S1P signaling to regulate endothelial cell behavior and vascular development Jilishitz, Irina 2016 Theses MorphogenesisGrowth factorsNeovascularizationEndothelial cellsMolecular biologyBiochemistry
15. Combined Biosynthetic and Synthetic Production of Valuable Molecules: A Hybrid Approach to Vitamin E and Novel Ambroxan Derivatives Adanve, Bertrand Tankpinou 2015 Theses Organic compounds--SynthesisVitamin ESynthetic biologyChemistryBiochemistry
16. Cryo-electron microscopy and single particle reconstructions of the Leishmania major ribosome and of the encephalomyocarditis virus internal ribosome entry site bound to the 40S subunit Jobe, Amy Beth 2017 Theses Electron microscopyRibosomesLeishmaniaRNACryoelectronicsBiologyBiochemistryBiophysics
17. Cryo-electron microscopy studies of dynamical features of ribosomes during the translation process Sun, Ming 2016 Theses BiophysicsProteins--StructureRibosomes--StructureRibosomesCryoelectronicsBiologyBiochemistry
18. CysZ: Structural and Functional Studies of a Novel Sulfate Transport Protein Assur, Zahra 2013 Theses CytologyCarrier proteinsBiochemistryBiophysics
19. Design and Synthesis of 3'-Oxygen-Modified Cleavable Nucleotide Reversible Terminators for Scarless DNA Sequencing by Synthesis Hsieh, Min-Kang 2018 Theses Chemical engineeringBiochemistryBiomedical engineeringNucleotide sequence
20. Development of Single Molecule Electronic SNP Assays using Polymer Tagged Nucleotides and Nanopore Detection Cho, Youngjin 2018 Theses BiochemistryBiomedical engineeringNanoporesSingle nucleotide polymorphisms
21. Development of Trimethoprim Chemical Tags for Single Molecule Imaging in Live Cells Wang, Tracy Yuh 2015 Theses ChemistryBiochemistry
22. Directed Evolution of Protein Receptor Binding for Small Molecule Therapeutics Using Fluorescence Polarization Bannier, Sean David 2021 Theses ChemistryBiochemistryBiophysicsTetracylcinesProtein bindingPolarization (Light)Yeast
23. Discovery of Novel Ferroptosis Regulators Using Genetic and Lipidomic Analyses Bezjian, Carla Tara 2021 Theses CytologyMolecular biologyBiochemistryCell deathGenetic regulationPhospholipids
24. Dynamic Nuclear Polarization with Biradical Affinity Reagents Rogawski, Rivkah 2018 Theses BiophysicsChemistryBiochemistryPolarization (Nuclear physics)Biradicals
25. Electrodeposition and Electroless Deposition of Copper in Interconnect Technology and Biotechnology Related Applications Sun, Xiaoxuan 2015 Theses Chemical engineeringChemistryBiochemistry
26. Engineering a Repeats-in-Toxin Scaffold for Stimulus-Responsive Biotechnology Applications Dooley, Kevin P. 2014 Theses Proteins--StructureChemical engineeringBiochemistryBiomedical engineering
27. Engineering Electron Transfer Processes in Oxidoreductases: Applications in Biocatalysis Ozbakir, Harun Ferit 2017 Theses Chemical engineeringBiochemistryOxidoreductasesBiocatalysis
28. Examining the Effects of D-Amino Acids on Translation Fleisher, Rachel Chaya 2016 Theses Messenger RNAAmino acidsAmino acid sequenceRibosomesBiochemistryChemistry
29. Expanding Silane-Mediated Coupling Methodologies for the Formation of Medicinally Relevant Structural Motifs Hughes, Isaac 2020 Theses Chemistry, OrganicBiochemistrySilane compoundsSilicates
30. Exploring an Interface Between Synthetic Chemistry and Chemical Biology: The Synthesis of Complex Natural Products and Novel Chemical Probes Thomas, Stephen Basil 2015 Theses Natural products--SynthesisBiochemistryChemistry, OrganicOrganic compounds--SynthesisChemistry
31. Ferroptosis: A Novel Form of Cancer Cell Death Induced by the Small Molecule Erastin Lemberg, Kathryn 2011 Theses BiologyBiochemistryChemistryApoptosisCell deathCancer
32. Gates and Latches: the mechanochemistry of ATP binding in kinesin 1 and Eg5 Behnke-Parks, William M. 2011 Theses BiologyBiophysicsBiochemistryKinesinMechanical chemistryCell division
33. Genetic Mechanisms of Regulated Stochastic Gene Expression Horta, Adan 2019 Theses NeurosciencesBiochemistryGeneticsOlfactory receptor genesGene expressionCadherinsHuman genetics--Variation
34. Harnessing Growth Selections in Saccharomyces cerevisiae for Biological Engineering Harton, Marie Deborah Gaynelle 2015 Theses Natural selectionSaccharomyces cerevisiae--GeneticsBiomedical engineeringBiochemistry
35. How to steal ribosomes: structural studies of two different internal ribosome entry sites Neupane, Ritam 2021 Theses BiochemistryBiophysicsVirologyRibosomesEukaryotic cells
36. I: Catalytic Direct C-H Arylation of Pyrazoles. II: Toward Modulation of Neuroplasticity with Small Molecules Jacques, Teresa 2013 Theses ChemistryChemistry, OrganicBiochemistryPyrazolesArylationNeuroplasticity
37. Identification and Biophysical Characterization of Small Molecules Modulating Protein Disulfide Isomerase in Neurodegenerative Diseases Kaplan, Anna 2015 Theses Nervous system--DegenerationNeuroprotective agentsProtein disulfide isomeraseBiophysicsBiochemistryBiology
38. Integration of EGFR and LIN-12/Notch signaling in Vulval Precursor Cell fate specification in Caenorhabditis elegans Underwood, Ryan 2018 Theses BiochemistryMetazoaCell interactionCellular signal transductionBiophysics
39. Investigating the role of the RNA binding protein TDP-43 in Amyotrophic Lateral Sclerosis using animal and cell-based models of disease Lehrer, Helaina 2015 Theses Molecular biologyNeurosciencesBiochemistry
40. Investigation of Ribonuclease HI handle region dynamics using Solution-state nuclear magnetic resonance spectroscopy, Molecular Dynamic simulations and X-ray crystallography Martin, James Arthur 2020 Theses BiophysicsBiochemistryHIV (Viruses)Mouse leukemia virusesRNAEndonucleasesNuclear magnetic resonance spectroscopy
41. Learning from cadherin structures and sequences: affinity determinants and protein architecture Felsovalyi, Klara 2014 Theses Protein bindingCadherinsBiochemistryBioinformaticsBiophysics
42. Ligand-Protein Interactions in Cytochromes Catalano, Jaclyn 2011 Theses ChemistryBiochemistryBiophysics
43. Lipids on Fire: Identifying and Targeting Subcellular Membranes that Drive Ferroptosis Von Krusenstiern, Alfred Nikolai 2022 Theses BiochemistryCell deathLipids--PeroxidationCancer--TreatmentEndoplasmic reticulumFatty acidsRaman effectConfocal fluorescence microscopy
44. Liver X Receptor cis-Repression and Cholesterol Efflux Restrain Innate Immunity and Coronary Artery Disease Thomas, David George 2019 Theses CytologyMolecular biologyBiochemistryAtherosclerosis--PreventionImmunityNuclear receptors (Biochemistry)
45. Mammalian translation termination intermediates captured using PDMS microfluidics-based time-resolved cryo-EM (TRCEM) Dadhwal, Prikshat 2024 Theses BiologyBiochemistryBiophysicsEukaryotic cells--GeneticsGenetic translationRibosomesSilicaCryoelectronics
46. Mechanism of Transcription Arrest By The Nun Protein of Bacteriophage HK022 Vitiello, Christal Lourdes 2012 Theses MicrobiologyBiochemistryBiology
47. Mechanisms and therapeutic targeting of NT5C2 mutations in relapsed acute lymphoblastic leukemia Dieck, Chelsea 2019 Theses BiochemistryLymphoblastic leukemiaDrug resistanceOncologyMutation (Biology)Molecular biology
48. Mechanochemical Methods for Single Molecule Biochemistry and Studies of Thiol-Disulfide Exchange in Proteins Kosuri, Pallav 2012 Theses BiophysicsBiochemistryBiology
49. Membrane partitioning by Flotillin-1 facilitates amphetamine-induced dopamine transporter activity Fong, Wendy Mei 2017 Theses BiochemistryNeurosciencesCytologyCell membranesCarrier proteins
50. MEMS-based temperature-dependent characterization of biomolecular interactions Wang, Bin 2012 Theses Mechanical engineeringBiochemistry
51. Molecular Approaches to Targeting Oncogenic KRAS and Ferroptosis Feng, Huizhong 2019 Theses Molecular biologyBiochemistryCytologyBiochemical markersCancerCell death
52. Molecular Basis for the Recognition of the Regulatory Stem-loop Structures in Eukaryotic Messenger RNAs Tan, Dazhi 2014 Theses Messenger RNARNA-protein interactionsEukaryotic cellsBiologyBiochemistryMolecular biology
53. Molecular Insights into Ferroptosis as a Therapeutic Target for Huntington’s Disease Daniels, Jacob D. 2022 Theses PharmacologyBiochemistryHuntington's disease--TreatmentCell deathProbucol
54. Molecular Mechanisms Controlling Synaptic Vesicle Fusion Radoff, Daniel Todd 2011 Theses BiochemistrySynaptic vesiclesCell membranesMembrane proteins
55. Nanoscale Electrical and Coarse-grained Molecular Dynamics Studies of Influenza Hemagglutinin-mediated Membrane Fusion Pores Alcott, Brett Eugene 2017 Theses BiophysicsBiochemistryVirologyMolecular dynamicsMembrane fusion
56. Non-canonical WDR33 Isoforms: Characterization, Regulation, and Functional Significances in STING-Mediated Innate Immune Responses Liu, Lizhi 2023 Theses Molecular biologyImmunologyBiochemistryAmino acid sequenceGene expressionMessenger RNAOligomerizationInterferon
57. Novel Functions for Dynein Adaptor RILP in Neuronal Autophagy Khobrekar, Noopur V. 2021 Theses BiologyNeurobiologyBiochemistryDyneinAutophagic vacuolesCell organelles
58. Novel functions of C9ORF72, a gene involved in ALS/FTD Fomin, Vitalay 2019 Theses BiologyBiochemistryGeneticsCytologyAmyotrophic lateral sclerosisFrontotemporal dementiaGene expression
59. Novel Methods for the Ribosomal Incorporation of β-Amino Acids Sanguineti, Gabriella 2016 Theses Amino acidsBiochemistry--MethodologyPeptides--SynthesisBiochemistry
60. Novel Regulatory Mechanisms of Cytoplasmic Dynein: A Role for the Complex Base Weil, Sarah J. 2013 Theses BiologyBiochemistry
61. Nucleosome Curtains and their application to the study of DNA condensation by condensin Moevus, Corentin Jean 2019 Theses BiochemistryBiophysicsDNACondensed matter
62. Oxidative Folding in Bacteria: Studies Using Single Molecule Force Spectroscopy Kahn, Thomas 2016 Theses Protein foldingOxidoreductasesEscherichia coli--PhysiologyOxidationBiophysicsBiochemistry
63. Pathways for kidney triglyceride accumulation Scerbo, Diego 2018 Theses BiologyBiochemistryNutritionTriglyceridesKidneys--Diseases
64. P-REX2 PH Domain Inhibition of PTEN Regulates Transformation, Insulin Signaling, and Glucose Homeostasis Hodakoski, Cindy Marie 2012 Theses BiologyBiochemistry
65. Protein Structure Dynamics and Function at Micelle and Particle Interfaces Chin, Michael 2015 Theses ChemistryBiochemistryBiophysics
66. PTEN affects gene expression and histone modifications and plays a role in the regulation of transcription Steinbach, Nicole 2017 Theses CytologyBiochemistryOncologyGene expressionGenetic transcription
67. PTEN-LONG, a translational variant of the canonical tumor suppressor PTEN Hopkins, Benjamin 2013 Theses BiologyBiochemistryTumor suppressor proteinsAdenocarcinomaPancreas--Cancer--Research
68. Regulation of alternative splicing and its connections to cancer Chen, Mo 2011 Theses BiologyMolecular biologyBiochemistryRNA splicingPyruvate kinaseCancer cellsExons (Genetics)Mammals--Genetics
69. Regulation of Release Factor 2 in Non-canonical Translation Pathways Huang, Bridget Yih Jiin 2017 Theses Bacterial proteinsRibosomesBiochemistryProteins--SynthesisBiophysics
70. Regulation Of Retroviral Silencing In Different Cell Types Wang, Cheng 2015 Theses RetrovirusesCellsMouse leukemia virusesBiochemistryVirology
71. Reprogramming protein synthesis for cell engineering Anzalone, Andrew Vito 2015 Theses Proteins--SynthesisBioengineeringAmino acids--BiotechnologyRNA-protein interactionsSynthetic biologyBiochemistryChemistry, OrganicBiologyMolecular biology
72. Resonance-energy-transfer-based fluorescence imaging and free energy perturbation calculation Xu, Fang 2018 Theses Chemistry, Physical and theoreticalProtein-protein interactionsFluorescenceEnergy transferBiochemistry
73. Role of motor neuron autophagy in a mouse model of Amyotrophic Lateral Sclerosis Rudnick, Noam Daniel 2016 Theses Motor neuronsAutophagic vacuolesAmyotrophic lateral sclerosisNeurosciencesBiochemistryMedicine
74. RPGRIP1L and FTO – genes implicated in the effects of FTO intronic sequence variants on food intake – also affect adipogenesis and adipocyte biology. Martin-Carli, Jayne Frances 2017 Theses BiochemistryCytologyMolecular biologyObesity--Genetic aspects
75. Shared Molecular Features of Inherited and Sporadic ALS/FTD Conlon, Erin Grace 2018 Theses BiochemistryGeneticsNeurosciencesAmyotrophic lateral sclerosisFrontotemporal dementiaMolecular biology
76. Single-Molecule Analysis of Ribosome and Initiation Factor Dynamics during the Late Stages of Translation Initiation MacDougall, Daniel David 2012 Theses Genetic translationBiochemistryRibosomesBiophysics
77. Single-molecule observations of hRPA, RAD51, and RAD52 on single-stranded DNA Ma, Chu Jian 2017 Theses BiochemistryBiophysicsDNA replicationGenetic recombinationMolecular biology
78. Small molecules modulating ferroptosis in disease models Tan, Hui 2023 Theses BiochemistryCell deathCancer--TreatmentDiseases--EtiologyHuntington's diseaseLymphomasKidneys--DiseasesNervous system--Diseases
79. Solving Challenging Structures using Single-Particle Cryogenic Electron Microscopy Tan, Yong Zi 2019 Theses BiochemistryBiophysicsElectron microscopyMacromolecules--StructureRibosomesMembrane proteinsCytology--Technique
80. Structural Analyses of the Transient Receptor Potential Channels TRPV3 and TRPV6 McGoldrick, Luke Lawrence Reedy 2019 Theses BiochemistryMolecular biologyTRP channelsStructure-activity relationships (Biochemistry)Ion channels
81. Structural and Biochemical Characterizations of the Symplekin-Ssu72-CTD Complex in Pre-mRNA 3' end Processing Xiang, Kehui 2013 Theses BiochemistryGenetic transcriptionRNA polymerasesBiologyMolecular biology
82. Structural and Biochemical Studies of the Human pre-mRNA 3’-end Processing Complex Hamilton, Keith 2021 Theses BiochemistryBiophysicsMessenger RNA--AnalysisMutagenesis
83. Structural and biophysical characterization of protocadherin extracellular regions Wolcott, Holly Noelle 2014 Theses BiochemistryBiophysics
84. Structural and Biophysical Studies of Hair Cell Mechanotransduction Proteins Dionne, Gilman 2020 Theses BiochemistryBiophysicsHair cellsProteinsCellular signal transduction--Research
85. Structural and biophysical studies of the Drosophila melanogaster Dpr and DIP families Cosmanescu, Filip 2018 Theses BiochemistryNeurosciencesBiophysicsDrosophila melanogasterNeurons
86. Structural and functional characterization of the retinol-binding protein receptor STRA6 Costabile, Brianna Kay 2021 Theses BiochemistryEpitheliumVitamin A deficiencyVitamin APlacentaChoroid plexusElectron microscopyCalmodulin--Physiological effectZebra danio
87. Structural and Functional Investigation of Bacterial Membrane Biosynthesis Belcher Dufrisne, Meagan Leigh 2018 Theses BiochemistryBacterial cell walls--SynthesisPhosphoinositidesBiosynthesisEnzymesTuberculosis--TreatmentPeptidoglycansMycoplasmataceae
88. Structural and Functional Studies of Biotin-Dependent Carboxylases Huang, Christine S. 2013 Theses BiochemistryBiophysics
89. Structural and Functional Studies of CNG channels Hu, Zhengshan 2023 Theses BiologyBiochemistryBiophysicsCyclic nucleotides--AnalysisIon channelsCryoelectronicsElectron microscopy
90. Structural and Functional Studies of TRPML1 and TRPP2 Benvin, Nicole Marie 2017 Theses BiologyBiochemistryBiophysicsTRP channelsProteins--Structure
91. Structural and functional studies on the regulation of pyruvate carboxylase by the bacterial second messenger cyclic-di-AMP Choi, Philip H. 2017 Theses Enzymes--StructureListeria monocytogenesEnzymesPyruvate carboxylaseBiochemistryMicrobiology
92. Structural Investigation of Plasmodium falciparum Chloroquine Resistance Transporter in the Context of Anti-Malarial Drug Resistance Kim, Jonathan Young 2019 Theses BiochemistryMalariaDrug resistanceAntimalarialsDrugs--Physiological transport
93. Structural Studies of a Mammalian Epithelial Calcium Channel Saotome, Kei 2016 Theses Calcium--Physiological effectBiochemistryTRP channelsCalcium channels
94. Structural Studies of the Fungal pre-mRNA 3'-end Processing Machinery Jurado, Ashley Rae 2015 Theses ProteinsRNA splicingScission (Chemistry)Messenger RNAMolecular biologyBiologyBiochemistry
95. Structural Studies of the Integrator Complex -- pre-UsnRNA 3'-end Processing Machinery Wu, Yixuan 2018 Theses BiologyBiochemistryCatalytic RNA
96. Structural studies of the yeast transcription termination complex Nrd1-Nab3-Sen1 Zhang, Yinglu 2019 Theses BiologyMolecular biologyBiochemistryRNA polymerasesGenetic transcription
97. Structural studies on bestrophin anion channels by cryogenic electron microscopy Owji, Aaron Paul 2022 Theses BiophysicsBiochemistryEye--PhysiologyChloride channelsKlebsiella pneumoniaeMammalsMutagenesis
98. Structure and Function of a Transposon-Encoded CRISPR-Cas System Halpin-Healy, Tyler Sheehan 2021 Theses BiochemistryBiophysicsMolecular biologyVibrio choleraeRNADNA
99. Structure and Function of Glutamate Receptor-Like Channels (GLRs) Green, Marriah Noel 2023 Theses NutritionBiochemistryBiophysicsGlutamic acidLigand binding (Biochemistry)Arabidopsis thalianaCell receptors
100. Structure and Neutralization of Viral Fusion Proteins Casner, Ryan Gavin 2023 Theses BiochemistryCOVID-19 (Disease)ImmunoglobulinsCryoelectronicsVaccines--Design