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1. Identifying the origin and mechanisms of pathological angiogenesis in neuroinflammatory diseases

Shahriar, Sanjid
2022
Theses
NeurosciencesNervous system--Diseases--EtiologyPathologyNeovascularization

2. CDX2 as a Predictive Biomarker of Drug Response in Colon Cancer

Raab, William
2021
Theses
OncologyColon (Anatomy)--Cancer--TreatmentPaclitaxel--Therapeutic useHomeobox genesMutagenesis

3. Epitranscriptomic Alterations in Alzheimer’s Disease: The Role of MicroRNA Methylation in the Regulation of Tau Proteostasis

Kim, Yoon Anna
2021
Theses
NeurosciencesPathologyMolecular biologyAlzheimer's disease--Genetic aspectsMicroRNAMethyltransferasesNervous system--DegenerationPhosphorylationDrosophila--GeneticsRats--GeneticsMice--Genetics

4. Microproteins and Epigenetic Remodeling in Cancer and Aging

Quinn, Stuart Aidan
2021
Theses
GeneticsLeukemiaAgingCancer--Gene therapyPolypeptidesAmino acidsHematopoietic stem cellsEpigenetics

5. Non-apoptotic Caspase-8 Signaling Mediates Retinal Angiogenesis

Johnson, Kendra Vincia
2021
Theses
NeurosciencesCytologyMolecular biologyRetina--DiseasesRetina--Blood-vesselsNeovascularizationRetinal degeneration--Animal models

6. α-Synuclein Autoimmunity in Parkinson’s Disease

Garretti, Francesca
2021
Theses
NeurosciencesImmunologyParkinson's disease--PathophysiologyParkinson's disease--TreatmentMiceAutoimmunity

7. Systemic Regulation of Cancer Metastasis

Zhong, Timothy James
2021
Theses
OncologyImmunologyMetastasisBreast--CancerCachexiaTumorsLymphocytes

8. Therapeutic strategies targeting FUS toxicity in amyotrophic lateral sclerosis: from a novel mouse model of disease to a first-in-human study

Korobeynikov, Vlad
2021
Theses
PathologyMedical sciencesNeurosciencesAmyotrophic lateral sclerosisRNA-protein interactionsDNA repairCentral nervous system--DiseasesMice--GeneticsHuman genetics

9. The Role of CtIP in Lymphocyte Development and Lymphomagenesis

Wang, Xiaobin
2021
Theses
DNA damageDNA repairOncologyLymphocytesLymphomas

10. The spatial distribution of cortical interneurons: the role of clustered protocadherins

Gallerani, Nicholas Edmund
2021
Theses
NeurosciencesDevelopmental biologyCerebral cortexInterneuronsMiceGenetics

11. The autophagosomal perspective: Tissue-specificity and cell-specificity of the autophagic response to starvation in vivo

Yang, Young Joo
2020
Theses
Molecular biologyBioinformaticsVeterinary medicineAutophagic vacuoles

12. Characterization of Endogenous Hematopoietic Stem Cells in Their Native Unperturbed State

Upadhaya, Samik K.
2019
Theses
ImmunologyBiologyHematopoietic stem cells

13. Investigations of 12α-Hydroxylated Bile Acid Signaling in Intestinal Organoids

Ahmad, Tiara Rinjani
2019
Theses
PathologyPhysiologyMolecular biologyBile acids--MetabolismIntestines--Metabolism

14. Microtubule Dynamics in Tau-dependent Amyloid Beta Synaptotoxicity

Qu, Xiaoyi
2019
Theses
CytologyNeurosciencesAmyloid beta-proteinMicrotubulesAlzheimer's diseaseAlzheimer's disease--Pathophysiology

15. Nucleosome Curtains and their application to the study of DNA condensation by condensin

Moevus, Corentin Jean
2019
Theses
BiochemistryBiophysicsDNACondensed matter

16. Unbiased Expression Profiling Identifies a Novel Notch Signaling Target RND1 as Regulator of Angiogenesis

Du, Jing
2019
Theses
Molecular biologyNeovascularizationRho GTPasesCellular signal transduction

17. Biomarkers of Alzheimer-Associated Endosomal Dysfunction

Neufeld, Jessi
2018
Theses
PathologyCytologyNeurosciencesEndosomesAlzheimer's diseaseBiochemical markers

18. Phosphorylation dependent structural function of DNA-PKcs in DNA repair and hematopoiesis

Crowe, Jennifer Lauryn
2018
Theses
Molecular biologyBiologyImmunologyPhosphorylationHematopoiesisDNA repair

19. The critical role of cysteine import and metabolism in pancreatic cancer

Badgley, Michael Alexander
2018
Theses
OncologyBiologyCytologyCysteinePancreas--Cancer

20. The Function of Peroxisome Proliferator-Activated Receptor-Gamma in the Urothelium

Liu, Chang
2018
Theses
BiologyPathologyCytologyEpitheliumUrinary organs