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1. A genetically-encoded biosensor and a conditional gene expression system for investigating Notch activity in vivo

Shaffer, Justin Matthew
2022
Theses
Developmental biologyGeneticsGene expressionCell interactionCaenorhabditis elegans--GeneticsExons (Genetics)

2. Analysis of Conformational Continuum and Free-energy Landscapes from Manifold Embedding of Single-particle Cryo-EM Ensembles of Biomolecules

Seitz, Evan Elliott
2022
Theses
Molecular biologyBiomoleculesElectron microscopy—Data processingMachine learningRiemannian manifoldsGibbs' free energyPath analysis (Statistics)RibosomesCOVID-19 (Disease)--Data processing

3. Development of genetically intact bioengineered spores of Bacillus subtilis

Flores Quijano, Juan Manuel de Jesus
2022
Theses
BiologyBacillus subtilis--GeneticsPlasmids--GeneticsBiotechnologyNatural pesticidesProbiotics

4. Expression and Functional Analyses of the Entire Cadherin Gene Family in C. elegans

Majeed, Maryam
2022
Theses
BiologyNeurosciencesCaenorhabditis elegans--GeneticsGene expression

5. Nucleolar transcription and its connections to nucleolar homeostasis and mitochondrial stress responses

Feng, Shuang
2022
Theses
Molecular biologyNucleic acidsHomeostasisMitochondriaCarcinogenesisNervous system--Diseases

6. Understanding and Engineering Multicomponent Living Systems: Examples from Synthetic Genomics and Engineered Living Materials

McBee, Andrew Ross MacKay
2022
Theses
BiologySynthetic biologyGenomicsMetazoaAmino acidsValineMycelium

7. A Comparative Analysis of Genome Rearrangement in Ciliates

Feng, Yi
2021
Theses
BiologyBioinformaticsEvolution (Biology)Gene rearrangementCiliata--GeneticsEuplotesGenetic code

8. Broad-scale variation in human genetic diversity levels is predicted by purifying selection on coding and non-coding elements

Murphy, David
2021
Theses
GeneticsEvolution (Biology)BiologyHuman genomeBiodiversity

9. Characterizing molecular drivers of clinical outcome in pediatric acute leukemias by systems biology and machine learning

Alloy, Alexandre Paul
2021
Theses
BioinformaticsLeukemia--Genetic aspectsLeukemia in childrenMachine learningAcute leukemia

10. Disentangling mutation and selection in human genetic variation: promises and pitfalls

Agarwal, Ipsita
2021
Theses
BiologyGeneticsEvolution (Biology)Mutation (Biology)Human genomeExomes