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1. Abeta42 oligomers trigger synaptic loss through AMPK-dependent activation of mitochondrial fission and mitophagy

Lee, Annie
2018
Theses
CytologyNeurosciencesAlzheimer's disease--PathogenesisSynapsesMitochondriaOligomersMolecular biology

2. Actin Cable Function and Regulation in the Budding Yeast, Saccharomyces cerevisiae

Lipkin, Thomas Gregory Karney
2011
Theses
CytologyMicrobiologyMolecular biology

3. A functional role for transfer RNA-derived microRNAs in human B cells

Maute, Roy Louis
2013
Theses
Molecular biology

4. Alcohol alters the expression of Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptors (SNAREs) and spontaneous γ-Aminobutyric Acid (GABA) release...

Varodayan, Florence Prabha
2013
Theses
NeurosciencesMolecular biology

5. A Mechanism of Mechanotransduction Mediated by the Primary Cilium

Lee, Kristen Lauren
2014
Theses
Cells--Mechanical propertiesBones--GrowthBiomedical engineeringMolecular biology

6. Analysis of Oncogenic Signal Transduction with Application to KRAS Signaling Pathways

Broyde, Joshua
2018
Theses
BioinformaticsBiometryMolecular biologyCancer--Molecular aspectsCellular signal transductionOncology

7. Analysis of The RING Domain And BRCT Repeats of BRCA1

Reid, Latarsha
2011
Theses
BiologyMolecular biologyGenetics

8. Analysis of Ureteric Bud Morphogenesis by Reassociation of Fetal Kidney Cells

Leclerc, Kevin
2015
Theses
KidneysMetalloproteinasesExtracellular matrixMorphogenesis--Molecular aspectsGeneticsMolecular biology

9. A p53-independent role for MDM2-MDMX in cell cycle progression

Klein, Alyssa Michelle
2021
Theses
CytologyMolecular biologyBiochemistryCancerMutation

10. A Study of the Mechanism of Motor Neuron Death in Amyotrophic Lateral Sclerosis

Politi, Kristin Ann
2017
Theses
Molecular biologyBiologyNeurosciencesAmyotrophic lateral sclerosisMotor neurons

11. Asymmetric Cell Division in the Generation of Immunity and Tolerance

Yen, Bonnie
2018
Theses
ImmunologyCell divisionImmunological toleranceMolecular biology

12. A Targetable GATA2-IGF2 Axis Confers Aggressiveness in Chemotherapy Resistant Prostate Cancer

Vidal, Samuel J.
2015
Theses
Molecular biologyOncology

13. Atf5 Links Olfactory Receptor Induced Stress Response to Proper Neuronal Function

Kahiapo, Jerome Keoki
2020
Theses
CytologyBiochemistryMolecular biologyOlfactory receptor genesSmellSensory neuronsMammals

14. Building a Genetic System in Yeast to Search for High Affinity Proteins in Sequence Space

Merguerian, Matthew Douglas
2013
Theses
Molecular biologyBiochemistryCytology

15. Cell-Specific Responses Redefine Acute Kidney Injury

Xu, Katherine
2018
Theses
Molecular biologyMedicineMicrobiologyAcute renal failureKidneys--Wounds and injuries

16. Characterization ofAthsq1, an Atherosclerosis Modifier Locus on Mouse Chromosome 4:

Kuo, Chao-Ling
2011
Theses
Medical sciencesGeneticsMolecular biology

17. Characterization of Gf a Drosophila trimeric G protein alpha subunit

Quibria, Naureen
2012
Theses
GeneticsCytologyMolecular biology

18. Characterizing the Mechanism of Tumor Suppression by PBRM1 in Clear Cell Renal Cell Carcinoma

Schoenfeld, David Aaron
2015
Theses
Renal cell carcinomaCancer--Genetic aspectsCarcinogenesisOncogenesAntioncogenesMolecular biologyOncology

19. Chloride Intracellular Channel (CLIC) proteins function to modulate Rac1 and RhoA downstream of endothelial G-protein coupled receptors signaling

Mao, De Yu
2019
Theses
PharmacologyChloride channelsMolecular biologyCytology

20. Chloride Intracellular Channels 1 and 4 function in distinct branches of S1P signaling to regulate endothelial cell behavior and vascular development

Jilishitz, Irina
2016
Theses
MorphogenesisGrowth factorsNeovascularizationEndothelial cellsMolecular biologyBiochemistry

21. Control of cellular plasticity during tissue remodeling in C. elegans

Aghayeva, Ulkar
2019
Theses
NeurosciencesMolecular biologyCaenorhabditis elegansTissue remodelingNeuroplasticity

22. Deciphering End Resection in Double-Strand Break repair in Saccharomyces cerevisiae

Chen, Huan
2015
Theses
Saccharomyces cerevisiaeDNA repairDNA damageBiologyMolecular biologyGenetics

23. Deciphering the Role of p24 Proteins in COPII-mediated Protein Secretion

D'Arcangelo, Jennifer G.
2015
Theses
Endoplasmic reticulumMolecular geneticsProteins--SecretionCytologyMolecular biologyGenetics

24. Delineating the function, efficacy, and mechanism of a novel preclinical agent for the treatment of pancreatic ductal adenocarcinoma

Eberle-Singh, Jaime
2018
Theses
OncologyRenal cell carcinomaPancreas--CancerCancer--TreatmentMedical sciencesMolecular biology

25. Designer Exons Inform a Biophysical Model for Exon Definition

Arias, Mauricio A.
2013
Theses
Exons (Genetics)Molecular biologyBiophysicsMessenger RNABiology

26. Development of a genetically encoded site-specific fluorescent sensor of human cardiac voltage-gated sodium channel inactivation

Shandell, Mia
2018
Theses
PharmacologySodium channelsMolecular biologyBiosensors

27. Dissecting the molecular basis of PfCRT-mediated antimalarial drug resistance

Gabryszewski, Stanislaw J.
2016
Theses
Drug resistanceChloroquineMedical sciencesPlasmodium falciparumMicrobiologyMolecular biologyParasitology

28. Dissecting the non-canonical functions of p53 through novel target identification and p53 acetylation

Wang, Shang-Jui
2014
Theses
CytologyMolecular biology

29. Distinct Nuclear-Cytoskeletal LINCages Position the Nucleus for Homeostasis, Polarization and Migration

Zhu, Ruijun
2017
Theses
CytologyBiologyCell nucleiMolecular biology

30. DNA Repair Capacity as a Marker of Breast Cancer Susceptibility

Kappil, Maya
2014
Theses
Molecular biologyEpigeneticsBreast--Cancer--EtiologyDNA repairGene expression

31. Elucidating the Biological Function of PWWP-Domain Containing Protein Complexes

Reddy, Bharat
2013
Theses
BiologyGeneticsMolecular biology

32. Endothelial Caspase-9 Activity Exacerbates Edema and Neuronal Dysfunction after Retinal Vein Occlusion

Avrutsky, Maria
2017
Theses
CytologyEdemaRetina--Blood-vesselsMolecular biology

33. Engineering Responsive Yeast Systems Using Fungal G-Protein-Coupled Receptors

Brisbois, James Ronald
2019
Theses
Molecular biologyChemistryCell interactionG proteins--ReceptorsYeast fungi

34. ER stress and lipid droplet-dependent proteostasis in response to lipid stress in yeast and a novel congenital muscular dystrophy

Garcia, Enrique Jose
2019
Theses
Molecular biologyCytologyLecithinMuscular dystrophyLipids

35. Evolutionary and Functional Diversity of Regulatory Factors and Sequences that Coordinate Gene Expression

Park, Jimin
2020
Theses
Biology--ClassificationMolecular biologyMicrobiologyGenetic regulationGene expressionDNA--Synthesis

36. Expanding the Toolkit for Metabolic Engineering

Ng, Yao Zong
2016
Theses
BioengineeringMolecular evolutionMicrobial genetic engineeringChemistryMolecular biology

37. From the End to the Middle: Regulation of Telomere Length and Kinetochore Assembly by the RNR Inhibitor SML1

Gupta, Amitabha
2012
Theses
Molecular biology

38. Function and tissue focus of daf-18/PTEN in maintaining blast cell multipotency and quiescence in Caenorhabditis elegans dauer larvae

Tenen, Claudia
2019
Theses
BiologyMultipotent stem cellsCaenorhabditis elegansMolecular biology

39. Generative Models for Synthetic Biology

Blazejewski, Tomasz
2020
Theses
BioinformaticsBiology--ClassificationMolecular biologySynthetic biologyMachine learningAmino acid sequence

40. Global Survey of Cell Death Mechanisms Reveals Metabolic Regulation of GPX4-Dependent Ferroptosis

Shimada, Kencihi
2015
Theses
HomeostasisMetabolismBioinformaticsPharmacologyCell deathMolecular biology

41. Hierarchical dynamics of individual RNA helix base pair formation and disruption

Hon, Jason J.
2017
Theses
ChemistryRNA--StructureField-effect transistorsMolecular biology

42. Identification and characterization of tissue-resident memory T cells in humans

Kumar, Brahma Vencel
2018
Theses
ImmunologyT cellsMedical sciencesMolecular biology

43. Identification of microRNA Biogenesis Regulators and Activity Modulators

Chung, Wei-Jen
2014
Theses
Cancer--Genetic aspectsMetastasisGenetic regulationRNABioinformaticsMolecular biology

44. Insights into MYC biology through investigation of synthetic lethal interactions with MYC deregulation

Sato, Mai
2014
Theses
Molecular biologyGeneticsPathology

45. Integrating psychosocial stress into children’s molecular epidemiology research: An investigation of flame retardants, telomeres and neuroendocrine development

Cowell, Whitney J.
2018
Theses
EpidemiologyEnvironmental healthMolecular biologyMolecular epidemiologyPolybrominated diphenyl ethersTelomereChild development

46. Interstitial Telomere Sequences Disrupt Break Induced Replication

Stivison, Elizabeth Anne
2019
Theses
GeneticsMolecular biologyTelomereDNA damageDNA replication

47. Investigating the Role of the Amyloid Precursor Protein in the Pathogenesis of Alzheimer's Disease

Lefort, Roger
2011
Theses
NeurosciencesMolecular biology

48. Investigating the role of the RNA binding protein TDP-43 in Amyotrophic Lateral Sclerosis using animal and cell-based models of disease

Lehrer, Helaina
2015
Theses
Molecular biologyNeurosciencesBiochemistry

49. Investigating the role of ubiquitin in endosomal sorting and processing of amyloid precursor protein

Williamson, Rebecca Lynn
2017
Theses
Amyloid beta-protein precursorUbiquitinEndosomesNervous system--DiseasesAmyloid beta-proteinNeurosciencesPathologyMolecular biology

50. Investigations into pathophysiologic mechanisms and treatment of primary mitochondrial diseases

Siegmund, Stephanie
2018
Theses
Molecular biologyMitochondrial pathologyRapamycinBiology