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1. Analysis of The RING Domain And BRCT Repeats of BRCA1

Reid, Latarsha
2011
Theses
BiologyMolecular biologyGenetics

2. Application and development of methods towards the target identification of biologically-active small molecules

SriRamaratnam, Rohitha
2011
Theses
ChemistryBiologyMoleculesBiochemistryBiochemical geneticsGene targeting

3. Avian Diversification in the Andes: Understanding Endemism Patterns and Historical Biogeography

Quintero Rivero, Maria Esther
2011
Theses
Evolution (Biology)BiologyZoology

4. Dynamics of Cellular Rigidity Sensing on the Micron and Sub-micron Scale

Ghassemi, Saba
2011
Theses
EngineeringBiology

5. Ferroptosis: A Novel Form of Cancer Cell Death Induced by the Small Molecule Erastin

Lemberg, Kathryn
2011
Theses
BiologyBiochemistryChemistryApoptosisCell deathCancer

6. Gates and Latches: the mechanochemistry of ATP binding in kinesin 1 and Eg5

Behnke-Parks, William M.
2011
Theses
BiologyBiophysicsBiochemistryKinesinMechanical chemistryCell division

7. Habitat modification and gene flow in Saimiri oerstedii: Landscape genetics, intraspecific molecular systematics, and conservation

Blair, Mary Elizabeth
2011
Theses
BiologyConservation biologyEcology

8. Investigating neurodegenerative diseases with small molecule modulators

Letso, Reka Rebecca
2011
Theses
BiologyChemistryNervous system--DegenerationCell deathMotor neurons--DiseasesSpinal muscular atrophy

9. Linking plant traits and herbivory in grassland biodiversity-ecosystem functioning research

Flynn, Dan F. B.
2011
Theses
EcologyBiology

10. Microtubules, Acetylation, and MEC-3 Regulated Genes in C. Elegans Mechanosensations

Keller, Charles Clifford
2011
Theses
BiologyNeurosciencesCaenorhabditis elegans--GeneticsMicrotubulesAcetylationTouchEukaryotic cellsGene expression

11. Native forest tree conservation in tropical agroforests: Case study of cacao farms in the Atlantic Forest of southern Bahia, Brazil

McGinty, Meghan Micheline
2011
Theses
EcologyBiologyEnvironmental law

12. Negative regulation of gene expression by the tumor suppressor p53

Barsotti, Anthony M.
2011
Theses
BiologyGene expressionAntioncogenesApoptosis

13. Phosphorylation of TASK-1 and its role in atrial arrhythmias

Harleton, Erin Rachel
2011
Theses
PharmacologyPhysiologyBiology

14. Physiology and Pathophysiology of Retinoid and Lipid Storage in Mouse Hepatic Stellate Cell Lipid Droplets

D'Ambrosio, Diana N.
2011
Theses
BiologyNutrition

15. Regulation of alternative splicing and its connections to cancer

Chen, Mo
2011
Theses
BiologyMolecular biologyBiochemistryRNA splicingPyruvate kinaseCancer cellsExons (Genetics)Mammals--Genetics

16. Regulation of Novel Biomedical Technologies

Heled, Yaniv
2011
Theses
Biotechnology--Law and legislationBiotechnology industries--Law and legislationMedical ethicsEmbryonic stem cells--Research--Law and legislationDonation of organs, tissues, etc.--Law and legislationBiopharmaceuticsBiomedical engineering--Government policyLawMedicineBiology

17. Requirement and regulation of actin polymerization during endocytosis

Basu, Roshni
2011
Theses
CytologyBiologyMicrobiology

18. Smoking and High-Fat Diet: Risk Factors Regulating Emphysema Formation

Golovatch, Polina
2011
Theses
Biology

19. Visualizing the One-Dimensional Diffusion of DNA Mismatch Repair Proteins at the Single-Molecule Level

Gorman, Jason
2011
Theses
BiologyBiochemistryBiophysicsDNA repairEukaryotic cells--Genetics

20. Basal-like breast cancer: modeling its initiation and characterizing novel EGFR variants

Pires, Maira Moura
2012
Theses
BiologyOncologyBreast--CancerTumor suppressor proteinsCarcinogenesis

21. Complex Regulation of Pax6 Neuronal Progenitors By Rb Family Members During Corticogenesis

Naglieri, Benedetta
2012
Theses
BiologyCerebral cortexTumor suppressor proteinsRetinoblastomaCarcinogenesis

22. Determining the Role of Trib3 in Neuronal Apoptosis

Zareen, Neela
2012
Theses
BiologyNeurosciences

23. Endosomal membrane dynamics underlying cell spreading: A role for the small GTPase Arf6

Bastien, Jayson I. L.
2012
Theses
Biology

24. Engineering the Repeats-in-Toxin Domain for Biotechnology Applications

Shur, Oren
2012
Theses
Chemical engineeringBiology

25. Gain-of-Function Effects of Mutant p53 Explored Using a Three-Dimensional Culture Model of Breast Cancer

Freed-Pastor, William Allen
2012
Theses
Biology

26. Impact of adult hippocampal neurogenesis on behavior

Denny, Christine
2012
Theses
BiologyNeurosciencesPsychologyDevelopmental neurobiologyHippocampus (Brain)--Growth

27. Integrin-Linked Kinase, ECM Composition, and Substrate Rigidity Regulate Focal Adhesion - Actin Coupling, Modulating Survival, Proliferation and Migration: Towards a Biophysical Cancer Biomarker

Chander, Ashok Coil
2012
Theses
BiologyCytologyBiophysics

28. Mechanism of Transcription Arrest By The Nun Protein of Bacteriophage HK022

Vitiello, Christal Lourdes
2012
Theses
MicrobiologyBiochemistryBiology

29. Mechanochemical Methods for Single Molecule Biochemistry and Studies of Thiol-Disulfide Exchange in Proteins

Kosuri, Pallav
2012
Theses
BiophysicsBiochemistryBiology

30. Mitochondrial Inheritance and Function in the Lifespan Control of Budding Yeast

McFaline Figueroa, Jose Ricardo
2012
Theses
CytologyBiologyMicrobiologyMitochondriaYeast--GrowthCell division

31. P-REX2 PH Domain Inhibition of PTEN Regulates Transformation, Insulin Signaling, and Glucose Homeostasis

Hodakoski, Cindy Marie
2012
Theses
BiologyBiochemistry

32. Analyzing Genomic Studies and a Screen for Genes that Suppress Information Loss During DNA Damage Repair

Pierce, Steven
2013
Theses
BiologyCytologyBioinformatics

33. A Novel Platform to Perform Cancer-Relevant Synthetic Dosage Lethality Screens in Saccharomyces cerevisiae

Dittmar, John
2013
Theses
BioinformaticsBiologyGenetics

34. Be Eaten to Stay Healthy: Elucidating the Mechanisms of Mitochondrial Quality Control by Mitophagy

de Vries, Rosa Leonora Andrea
2013
Theses
Mitochondrial pathologyCell physiologyNervous system--DegenerationPathologyNeurosciencesBiology

35. Computational Inferences of Mutations Driving Mesenchymal Differentiation in Glioblastoma

Chen, James C.
2013
Theses
Mutation (Biology)Mesenchymal stem cells--DifferentiationSystems biologyRetinoblastomaBioinformaticsGeneticsBiology

36. Designer Exons Inform a Biophysical Model for Exon Definition

Arias, Mauricio A.
2013
Theses
Exons (Genetics)Molecular biologyBiophysicsMessenger RNABiology

37. Dissecting genetic determinants of transcription factor activity

Lee, Eunjee
2013
Theses
BiologyBioinformatics

38. Elucidating the Biological Function of PWWP-Domain Containing Protein Complexes

Reddy, Bharat
2013
Theses
BiologyGeneticsMolecular biology

39. HDAC6 activity is required for efficient polarization and intracellular transport of organelles in directionally migrating cells

Salam, Ambar Asghar
2013
Theses
Biology

40. Leveraging Microtechnology to Study Multicellular Microvascular Systems and Macromolecular Interaction

Parsa, Hesam
2013
Theses
BiologyBiomedical engineeringMicrotechnologyDrugs--EffectivenessCancer cells--Effect of drugs on

41. Modulation of touch sensitivity in Caenorhabditis elegans

Chen, Xiaoyin
2013
Theses
NeurosciencesGeneticsBiology

42. Novel Regulatory Mechanisms of Cytoplasmic Dynein: A Role for the Complex Base

Weil, Sarah J.
2013
Theses
BiologyBiochemistry

43. PTEN-LONG, a translational variant of the canonical tumor suppressor PTEN

Hopkins, Benjamin
2013
Theses
BiologyBiochemistryTumor suppressor proteinsAdenocarcinomaPancreas--Cancer--Research

44. Role of Microtubule Motor Proteins in Adenoviral Infections

Scherer, Julian
2013
Theses
Biology

45. Serum Regulation of Inhibitor of DNA Binding/Differentiation 1 Expression by a BMP Pathway and BMP Responsive El

Lewis, Thera Cathy
2013
Theses
BiologyMolecular biology

46. Spatial, temporal and mechanistic characterization of apoptotic death in the developing subventricular zone

Marcolino, Bianca
2013
Theses
CytologyCell deathDevelopmental neurobiologyApoptosisNeurosciencesBiology

47. Structural and Biochemical Characterizations of the Symplekin-Ssu72-CTD Complex in Pre-mRNA 3' end Processing

Xiang, Kehui
2013
Theses
BiochemistryGenetic transcriptionRNA polymerasesBiologyMolecular biology

48. Studies of SV40-transformation and the Loss of Growth Factor Requirements

Powers, Robert Scott
2013
Theses
Biology

49. Temporal Processing by Caenorhabditis elegans Sensory Neurons

Kato, Saul Sen
2013
Theses
NeurosciencesBiologyBiophysics

50. The role of phospholipase D1 in trafficking and processing of amyloid precursor protein

Point du Jour, Kimberly Shauntae
2013
Theses
PathologyNeurosciencesBiology

51. Threonine Phosphorylation Regulates Two-Component Systems Involved in Cell Wall Metabolism

Goss, Lindsie Adela
2013
Theses
MicrobiologyBiology

52. Elucidating the roles of PARP1 and RBBP6 in the regulation of pre-mRNA 3' end processing

Campigli Di Giammartino, Dafne
2014
Theses
Biology

53. Establishment and Maintenance of Adult Stem Cell Identity: Specification of the Adult Copper Cell Region of the Drosophila Intestine

Driver, Ian
2014
Theses
Developmental biologyBiologyAdult stem cellsDrosophila

54. Gene regulatory factors that control the identities of specific neuron types in Caenorhabditis elegans

Zhang, Feifan
2014
Theses
GeneticsBiology

55. Heterogeneity and Context-Specificity in Biological Systems

Litvin, Oren
2014
Theses
BiologyBioinformaticsGenetics—ResearchBacterial diversity--Genetic aspectsGenetics--Mathematical models

56. Mechanisms for Taste Sensation of Carbonation

Yarmolinsky, David
2014
Theses
BiologyNeurosciences

57. Mechanisms Underlying Mitochondrial Quality Control and Cytokinesis in Budding Yeast

Alessi, Dana
2014
Theses
CytokinesisSaccharomyces cerevisiaeMitochondriaBiologyCytologyMolecular biology

58. Mid-channel proteolysis of the L-type voltage gated calcium channel and the potential role of amyloid-β precursor protein

Henckels, Kathryn
2014
Theses
BiologyNeurosciences

59. Molecular Basis for the Recognition of the Regulatory Stem-loop Structures in Eukaryotic Messenger RNAs

Tan, Dazhi
2014
Theses
Messenger RNARNA-protein interactionsEukaryotic cellsBiologyBiochemistryMolecular biology

60. p90 and UHRF1, Two Novel Regulators of the p53 Signaling Pathway

Dai, Chao
2014
Theses
Biology

61. Role of Autophagy and Peroxisome Proliferator-Activated Receptor Gamma2 in Hepatic Lipid Homeostasis

Conlon, Donna Marie
2014
Theses
NutritionBiology

62. Structural Studies of the Ryanodine Receptor and Its Binding Protein, Calstabin

Duvshani, Amit
2014
Theses
BiologyPhysiologyImmunosuppressive agentsRyanodine--ReceptorsHeart failureArrhythmia--PathophysiologyRapamycin

63. Structure Characterization of the 70S-BipA Complex Using Novel Methods of Single-Particle Cryo-Electron Microscopy

Ho, Danny Nam
2014
Theses
Bacterial proteinsElectron microscopyAntibacterial agentsCryoelectronicsBiologyBiophysics

64. Cell Memory in the Mitogen-Activated Protein Kinase Signaling Pathway

Lyashenko, Eugenia
2015
Theses
Mitogen-activated protein kinasesWeber-Fechner lawCellular control mechanismsBioinformaticsBiology

65. Characterization of motor pool selectivity of neuromuscular degeneration and identification of molecular correlates of disease resistance in Type I spinal muscular atrophy

Lee, Justin
2015
Theses
Spinal muscular atrophyNervous system--DegenerationNeuromuscular diseasesNeurosciencesPathologyBiology

66. Computational design, synthesis, and biological evaluation of small molecule anti-cancer therapeutics

Welsch, Matthew Ernest
2015
Theses
ChemistryMedicineBiology

67. Computational integration of genome-wide observational and functional data in cancer

Sanchez Garcia, Felix
2015
Theses
Computer scienceBioinformaticsBiology

68. Contributions of Activated Hepatic Stellate Cells to Hepatocarcinogenesis

Dapito, Dianne Helerie
2015
Theses
OncologyBiology

69. Cryo-EM and time-resolved cryo-EM studies on translation

Chen, Bo
2015
Theses
RibosomesProteins--SynthesisGenetic translationElectron microscopyBiophysicsBiology

70. Deciphering End Resection in Double-Strand Break repair in Saccharomyces cerevisiae

Chen, Huan
2015
Theses
Saccharomyces cerevisiaeDNA repairDNA damageBiologyMolecular biologyGenetics

71. FAK and SRC Kinases Maintain Integrin Activation During Endocytic Recycling to Polarize Adhesion Formation

Nader, Guilherme Pedreira de F.
2015
Theses
Protein kinasesFocal adhesion kinaseCell adhesion moleculesIntegrinsBiology

72. Identification and Biophysical Characterization of Small Molecules Modulating Protein Disulfide Isomerase in Neurodegenerative Diseases

Kaplan, Anna
2015
Theses
Nervous system--DegenerationNeuroprotective agentsProtein disulfide isomeraseBiophysicsBiochemistryBiology

73. Investigations of the neuro-molecular physiology of obesity using hypothalamic neurons derived from human pluripotent stem cells

Wang, Liheng
2015
Theses
HypothalamusObesityObesity--Physiological aspectsMolecular neurobiologyBiologyNutritionMolecular biology

74. Novel Roles of Ataxia Telangiectasia Mutated (ATM) in DNA Repair and Tumor Suppression

Yamamoto, Kenta
2015
Theses
Protein kinasesDNA repairDNA damageAntioncogenesAtaxia telangiectasiaBiologyCytologyPathology

75. Probing cell death mechanisms with chemical and genetic tools

Hayano, Miki
2015
Theses
CellsCytologyDeath (Biology)Cells--GrowthCells--Growth--RegulationCell deathBiology

76. Regulatory Logic of Pan-neuronal Gene Expression in Caenorhabditis elegans

Stefanakis, Nikolaos
2015
Theses
BiologyGenetics

77. Replication Protein A in the Maintenance of Genome Stability

Deng, Sarah
2015
Theses
DNA repairGenomesDNA-binding proteinsGeneticsBiologyMicrobiology

78. Reprogramming protein synthesis for cell engineering

Anzalone, Andrew Vito
2015
Theses
Proteins--SynthesisBioengineeringAmino acids--BiotechnologyRNA-protein interactionsSynthetic biologyBiochemistryChemistry, OrganicBiologyMolecular biology

79. Structural Studies of the Fungal pre-mRNA 3'-end Processing Machinery

Jurado, Ashley Rae
2015
Theses
ProteinsRNA splicingScission (Chemistry)Messenger RNAMolecular biologyBiologyBiochemistry

80. The Regulation of PREX2 by Phosphorylation

Barrows, Douglas Walker
2015
Theses
PhosphorylationInsulin--Mechanism of actionPhosphoinositidesBiologyBiochemistryPharmacology

81. Winning the cellular lottery: how proteins reach and recognize targets in DNA

Redding, Sy Eugene
2015
Theses
Promoters (Genetics)DNA-protein interactionsDNA-binding proteinsBiophysicsBiochemistryBiology

82. Behavior and Immunity in Drosophila melanogaster

Allen, Victoria Wing
2016
Theses
Circadian rhythmsAnimal behaviorDrosophila melanogaster--PhysiologyImmunityGeneticsBiology

83. Bone Marrow: A New Way of Modeling a Classic Organ

Churchill, Michael John
2016
Theses
Cell culture--TechniqueHematopoietic stem cellsAntibody-dependent cell cytotoxicityBone marrowBiologyImmunology

84. Connecting Cellular Redox State and Community Behavior in Pseudomonas aeruginosa PA14

Okegbe, Chinweike
2016
Theses
MorphologyOxidation-reduction reactionBiofilmsBiology

85. Cryo-electron microscopy studies of dynamical features of ribosomes during the translation process

Sun, Ming
2016
Theses
BiophysicsProteins--StructureRibosomes--StructureRibosomesCryoelectronicsBiologyBiochemistry

86. Cytoskeletal Regulation of Centromere Maintenance and Function in the Mammalian Cell Cycle

Liu, Chenshu
2016
Theses
MitosisCytoskeletonCentromereBiologyCytology

87. Developing New Strategies for Engineering Novel Natural Product Metabolic Pathways

Patenode, Caroline Anne
2016
Theses
BiocatalysisNatural products--SynthesisBiologyMicrobiologyChemistry

88. Dissecting the role of p53-mediated metabolic regulation in tumor suppression

Ou, Yang
2016
Theses
p53 antioncogeneTumor suppressor proteinsAntioncogenesMetabolism--Regulationp53 proteinBiologyOncologyCytology

89. Early intervention in a mouse model of childhood obesity: effects on brown adipose tissue function

Lerea, Jaclyn Sadie
2016
Theses
Brown adipose tissueBiotransformation (Metabolism)Obesity in childrenNutritionBiology

90. Influence of the cardiomyocyte niche on cell-based heart repair

Lee, Benjamin W.
2016
Theses
Cardiovascular system--Diseases--TreatmentHeart cellsHeart cells--Electric propertiesTissue engineeringCardiovascular system--DiseasesBiomedical engineeringMedicineBiology

91. Learning cell states from high-dimensional single-cell data

Levine, Jacob Harrison
2016
Theses
BioinformaticsCells--MeasurementMyeloid leukemiaCells--Computer programsBiologyOncology

92. Mechanisms of attention in visual cortex and the amygdala

Baruni, Jalal Kenji
2016
Theses
Amygdaloid bodyAttentionVisual perceptionVisual cortexNeurosciencesBiology

93. Modulation of Brain Chemistry with Small Molecule Probes: From Opioid to Growth Factor Signaling Systems

Gassaway, Madalee McKown
2016
Theses
Affective disordersOpioidsDepression, Mental--EtiologyBrain chemistryChemistryBiologyPharmacology

94. Molecular Dissection of Nde1's Role in Mitosis

Wynne, Caitlin Lazar
2016
Theses
MitosisCytologyMitosis--RegulationDyneinBiology

95. Nanostructured Platforms for Biological Study

Hu, Junqiang
2016
Theses
NanostructuresNanocomposites (Materials)NanotechnologyBiomedical materials--Mechanical propertiesImmunology--Equipment and suppliesNanostructured materialsImmunologyBiology

96. Physiology of Pseudomonas Aeruginosa Phenazine Production and Transport

Sakhtah, Hassan
2016
Theses
PhenazineMetabolitesBiofilmsPseudomonas aeruginosaBiology

97. PLATE-Seq: An Efficient and Scalable Method for Using RNA-Seq as a Primary Output in High Throughput Drug Screens

Ray, Forest
2016
Theses
Drugs--EffectivenessHigh throughput screening (Drug development)Gene expression--Research--MethodologyBiology

98. Role of Lysosomes in Nonshivering Thermogenesis

Lin, Yuxi
2016
Theses
Body temperatureBody temperature--RegulationObesity--Physiological aspectsLysosomesMolecular biologyBiology

99. The Role of SNORD116 in the Neuromolecular Pathogenesis of the Prader-Willi Syndrome

Cole, Lisa
2016
Theses
Gene expressionGenetic disordersBrain--AbnormalitiesPrader-Willi syndromeBiologyMolecular biologyEndocrinology

100. The Sustainment and Consequences of Cytosolic Calcium Signals in Osteocytes

Brown, Genevieve Nicole
2016
Theses
Calcium ionsIntracellular calciumBone cellsOsteocytesBiomedical engineeringBiologyBiomechanics