1. Application and development of methods towards the target identification of biologically-active small molecules SriRamaratnam, Rohitha 2011 Theses ChemistryBiologyMoleculesBiochemistryBiochemical geneticsGene targeting
2. Ferroptosis: A Novel Form of Cancer Cell Death Induced by the Small Molecule Erastin Lemberg, Kathryn 2011 Theses BiologyBiochemistryChemistryApoptosisCell deathCancer
3. Gates and Latches: the mechanochemistry of ATP binding in kinesin 1 and Eg5 Behnke-Parks, William M. 2011 Theses BiologyBiophysicsBiochemistryKinesinMechanical chemistryCell division
4. Regulation of alternative splicing and its connections to cancer Chen, Mo 2011 Theses BiologyMolecular biologyBiochemistryRNA splicingPyruvate kinaseCancer cellsExons (Genetics)Mammals--Genetics
5. Visualizing the One-Dimensional Diffusion of DNA Mismatch Repair Proteins at the Single-Molecule Level Gorman, Jason 2011 Theses BiologyBiochemistryBiophysicsDNA repairEukaryotic cells--Genetics
6. Mechanism of Transcription Arrest By The Nun Protein of Bacteriophage HK022 Vitiello, Christal Lourdes 2012 Theses MicrobiologyBiochemistryBiology
7. Mechanochemical Methods for Single Molecule Biochemistry and Studies of Thiol-Disulfide Exchange in Proteins Kosuri, Pallav 2012 Theses BiophysicsBiochemistryBiology
8. P-REX2 PH Domain Inhibition of PTEN Regulates Transformation, Insulin Signaling, and Glucose Homeostasis Hodakoski, Cindy Marie 2012 Theses BiologyBiochemistry
9. Novel Regulatory Mechanisms of Cytoplasmic Dynein: A Role for the Complex Base Weil, Sarah J. 2013 Theses BiologyBiochemistry
10. PTEN-LONG, a translational variant of the canonical tumor suppressor PTEN Hopkins, Benjamin 2013 Theses BiologyBiochemistryTumor suppressor proteinsAdenocarcinomaPancreas--Cancer--Research
11. Structural and Biochemical Characterizations of the Symplekin-Ssu72-CTD Complex in Pre-mRNA 3' end Processing Xiang, Kehui 2013 Theses BiochemistryGenetic transcriptionRNA polymerasesBiologyMolecular biology
12. Molecular Basis for the Recognition of the Regulatory Stem-loop Structures in Eukaryotic Messenger RNAs Tan, Dazhi 2014 Theses Messenger RNARNA-protein interactionsEukaryotic cellsBiologyBiochemistryMolecular biology
13. Identification and Biophysical Characterization of Small Molecules Modulating Protein Disulfide Isomerase in Neurodegenerative Diseases Kaplan, Anna 2015 Theses Nervous system--DegenerationNeuroprotective agentsProtein disulfide isomeraseBiophysicsBiochemistryBiology
14. Reprogramming protein synthesis for cell engineering Anzalone, Andrew Vito 2015 Theses Proteins--SynthesisBioengineeringAmino acids--BiotechnologyRNA-protein interactionsSynthetic biologyBiochemistryChemistry, OrganicBiologyMolecular biology
15. Structural Studies of the Fungal pre-mRNA 3'-end Processing Machinery Jurado, Ashley Rae 2015 Theses ProteinsRNA splicingScission (Chemistry)Messenger RNAMolecular biologyBiologyBiochemistry
16. The Regulation of PREX2 by Phosphorylation Barrows, Douglas Walker 2015 Theses PhosphorylationInsulin--Mechanism of actionPhosphoinositidesBiologyBiochemistryPharmacology
17. Winning the cellular lottery: how proteins reach and recognize targets in DNA Redding, Sy Eugene 2015 Theses Promoters (Genetics)DNA-protein interactionsDNA-binding proteinsBiophysicsBiochemistryBiology
18. Cryo-electron microscopy studies of dynamical features of ribosomes during the translation process Sun, Ming 2016 Theses BiophysicsProteins--StructureRibosomes--StructureRibosomesCryoelectronicsBiologyBiochemistry
19. Biology of maintenance and de novo methylation mediated by DNA methyltransferase-1 Yarychkivska, Olga 2017 Theses DNA--MethylationMethyltransferasesDNA replicationCell divisionGenomicsGeneticsBiochemistryBiology
20. Cryo-electron microscopy and single particle reconstructions of the Leishmania major ribosome and of the encephalomyocarditis virus internal ribosome entry site bound to the 40S subunit Jobe, Amy Beth 2017 Theses Electron microscopyRibosomesLeishmaniaRNACryoelectronicsBiologyBiochemistryBiophysics
21. Structural and Functional Studies of TRPML1 and TRPP2 Benvin, Nicole Marie 2017 Theses BiologyBiochemistryBiophysicsTRP channelsProteins--Structure
22. Allosteric Coupling, Nucleotide Binding and ATP Hydrolysis by Hsp70 Chaperones on a Structural Basis Wang, Wei 2018 Theses BiologyBiochemistryBiophysicsAllosteric regulationHeat shock proteins
23. Pathways for kidney triglyceride accumulation Scerbo, Diego 2018 Theses BiologyBiochemistryNutritionTriglyceridesKidneys--Diseases
24. Structural Studies of the Integrator Complex -- pre-UsnRNA 3'-end Processing Machinery Wu, Yixuan 2018 Theses BiologyBiochemistryCatalytic RNA
25. Novel functions of C9ORF72, a gene involved in ALS/FTD Fomin, Vitalay 2019 Theses BiologyBiochemistryGeneticsCytologyAmyotrophic lateral sclerosisFrontotemporal dementiaGene expression
26. Structural studies of the yeast transcription termination complex Nrd1-Nab3-Sen1 Zhang, Yinglu 2019 Theses BiologyMolecular biologyBiochemistryRNA polymerasesGenetic transcription
27. Novel Functions for Dynein Adaptor RILP in Neuronal Autophagy Khobrekar, Noopur V. 2021 Theses BiologyBiochemistryDyneinAutophagic vacuolesCell organelles
28. Structural and Functional Studies of CNG channels Hu, Zhengshan 2023 Theses BiologyBiochemistryBiophysicsCyclic nucleotides--AnalysisIon channelsCryoelectronicsElectron microscopy