1. Multiscale Structural and Biophysical Studies of Protein-Compound Interactions Trudeau, Stephen Joseph 2024 Theses BiophysicsProtein-protein interactionsMetabolitesThysanuraProteomics
2. Discovery of RNA-guided DNA integration by CRISPR-associated transposases Klompe, Sanne Eveline 2023 Theses Molecular biologyDNA-protein interactionsRNA-protein interactionsBacterial genomesImmunologyProkaryotesEscherichia coli
3. Structure and Neutralization of Viral Fusion Proteins Casner, Ryan Gavin 2023 Theses BiochemistryCOVID-19 (Disease)ImmunoglobulinsCryoelectronicsVaccines--Design
4. Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases King, Rebeca Teresa 2023 Theses GeneticsBiochemistryPersonalized medicineCRISPR (Genetics)DNA-binding proteinsNucleasesDouble-stranded RNA
5. Atf5 Links Olfactory Receptor Induced Stress Response to Proper Neuronal Function Kahiapo, Jerome Keoki 2020 Theses CytologyBiochemistryMolecular biologyOlfactory receptor genesSmellSensory neuronsMammals
6. Structural and Biophysical Studies of Hair Cell Mechanotransduction Proteins Dionne, Gilman 2020 Theses BiochemistryBiophysicsHair cellsProteinsCellular signal transduction--Research
7. Biomolecular NMR spectroscopy: Application to the study of the piRNA-pathway protein GTSF1, and backbone and side-chain spin relaxation methods development O'Brien, Paul 2019 Theses BiophysicsBiochemistryNuclear magnetic resonance spectroscopyProteins--StructureMolecular dynamics
8. Solving Challenging Structures using Single-Particle Cryogenic Electron Microscopy Tan, Yong Zi 2019 Theses BiochemistryBiophysicsElectron microscopyMacromolecules--StructureRibosomesMembrane proteinsCytology--Technique
9. Integration of EGFR and LIN-12/Notch signaling in Vulval Precursor Cell fate specification in Caenorhabditis elegans Underwood, Ryan 2018 Theses BiochemistryMetazoaCell interactionCellular signal transductionBiophysics
10. Mechanics of Gram-positive bacterial cell adhesion Echelman, Daniel Jay 2018 Theses BiophysicsNanoscienceMicrobiologyCell adhesion--Molecular aspectsGram-positive bacteriaCells--Mechanical properties
11. Structural and biophysical studies of the Drosophila melanogaster Dpr and DIP families Cosmanescu, Filip 2018 Theses BiochemistryNeurosciencesBiophysicsDrosophila melanogasterNeurons
12. Nanoscale Electrical and Coarse-grained Molecular Dynamics Studies of Influenza Hemagglutinin-mediated Membrane Fusion Pores Alcott, Brett Eugene 2017 Theses BiophysicsBiochemistryVirologyMolecular dynamicsMembrane fusion
13. Regulation of Release Factor 2 in Non-canonical Translation Pathways Huang, Bridget Yih Jiin 2017 Theses Bacterial proteinsRibosomesBiochemistryProteins--SynthesisBiophysics
14. RPGRIP1L and FTO – genes implicated in the effects of FTO intronic sequence variants on food intake – also affect adipogenesis and adipocyte biology. Martin-Carli, Jayne Frances 2017 Theses BiochemistryCytologyMolecular biologyObesity--Genetic aspects
15. Oxidative Folding in Bacteria: Studies Using Single Molecule Force Spectroscopy Kahn, Thomas 2016 Theses Protein foldingOxidoreductasesEscherichia coli--PhysiologyOxidationBiophysicsBiochemistry
16. PLATE-Seq: An Efficient and Scalable Method for Using RNA-Seq as a Primary Output in High Throughput Drug Screens Ray, Forest 2016 Theses Drugs--EffectivenessHigh throughput screening (Drug development)Gene expression--Research--MethodologyBiology
17. Structural Studies of a Mammalian Epithelial Calcium Channel Saotome, Kei 2016 Theses Calcium--Physiological effectBiochemistryTRP channelsCalcium channels
18. The Role of the Clustered Protocadherins in the Assembly of Olfactory Neural Circuits Mountoufaris, George 2016 Theses Olfactory nerveCadherinsNeural circuitryNeurosciences
19. Understanding complex biomolecular systems through the synergy of molecular dynamics simulations, NMR spectroscopy and X-Ray crystallography Zeiske, Tim 2016 Theses Molecular dynamics--Simulation methodsMolecular dynamics--Computer simulationNuclear magnetic resonance spectroscopyBiomolecules--Computer simulationX-ray crystallographyMacromolecules--StructureMolecular dynamicsBiophysicsBiochemistry
20. A Competition Mechanism for a Homeotic Neuron Identity Transformation in Caenorhabditis Elegans Gordon, Patricia Marie 2015 Theses Caenorhabditis elegansCaenorhabditis elegans--GeneticsCell divisionCell differentiationHomeobox genes
21. Learning from cadherin structures and sequences: affinity determinants and protein architecture Felsovalyi, Klara 2014 Theses Protein bindingCadherinsBiochemistryBioinformaticsBiophysics
22. Mechanisms for Taste Sensation of Carbonation Yarmolinsky, David 2014 Theses BiologyNeurosciences
23. Structural and biophysical characterization of protocadherin extracellular regions Wolcott, Holly Noelle 2014 Theses BiochemistryBiophysics
24. CysZ: Structural and Functional Studies of a Novel Sulfate Transport Protein Assur, Zahra 2013 Theses CytologyCarrier proteinsBiochemistryBiophysics
25. Genetic analysis of novel regulators of neuronal migration in Caenorhabditis elegans: the insulin/IGF-1 signaling pathway, a chromatin-binding factor ZFP-1 (AF10) and endogenous RNAi Kennedy, Lisa Michelle 2013 Theses Genetics
26. Thermal adaptation of conformational dynamics in ribonuclease H Stafford, Kate 2013 Theses Biochemistry
27. An Analysis of the Essential Chromatin Factor Zinc Finger Protein 1 (ZFP-1), and a Study of the Involvement of RNAi factors in Histone Processing in Caenorabditis Elegans Anastasiades Avgousti, Daphne Christina 2012 Theses BiochemistryBiophysicsCaenorhabditis elegansChromatinHistonesRNANucleosomes
28. Basal-like breast cancer: modeling its initiation and characterizing novel EGFR variants Pires, Maira Moura 2012 Theses BiologyOncologyBreast--CancerTumor suppressor proteinsCarcinogenesis
29. Mechanochemical Methods for Single Molecule Biochemistry and Studies of Thiol-Disulfide Exchange in Proteins Kosuri, Pallav 2012 Theses BiophysicsBiochemistryBiology
30. Structural Determinants of DNA-binding Specificity for Hox Proteins Liu, Peng 2012 Theses BiophysicsBioinformatics
31. Structure-Function Analysis of Hox-cofactor Interactions during Drosophila melanogaster Embryonic Development. Lelli, Katherine Marie 2012 Theses Genetics
32. Studies of a Site-Specific Recombination System and Analysis of New Modulators of Notch Signaling in C. elegans Vargas, Marcus L. 2012 Theses GeneticsMolecular biology
33. Towards the integration of structural and systems biology: structure-based studies of protein-protein interactions on a genome-wide scale Zhang, Qiangfeng Cliff 2012 Theses BioinformaticsBiophysicsSystems biologyProtein-protein interactionsGenomes
34. Molecular Mechanisms Controlling Synaptic Vesicle Fusion Radoff, Daniel Todd 2011 Theses BiochemistrySynaptic vesiclesCell membranesMembrane proteins
35. Using structure to explore the sequence alignment space of remote homologs Kuziemko, Andrew Stephen 2011 Theses BiophysicsHomology (Biology)Sequence alignment (Bioinformatics)