1. Genetic Pharmacotherapy as an Early CNS Drug Development Strategy: Testing Glutaminase Inhibition for Schizophrenia Treatment in Adult Mice Masson, Justine; Thomsen, Gretchen M.; Lin, Chyuan-Sheng; Merker, Robert J.; Gaisler-Salomon, Inna; Wang, Yvonne; Ernst, Rachel; Hen, Rene; Rayport, Stephen G.; Gellman, Celia; Mingote, Susana 2016 Articles Glutamic acidCentral nervous system--Effect of drugs onSchizophrenia--ChemotherapySchizophrenia--TreatmentMental healthMolecular biologyNeurosciencesMedicine
2. Global State Measures of the Dentate Gyrus Gene Expression System Predict Antidepressant-Sensitive Behaviors McCurdy, Richard D.; Dranovsky, Alex; Williams, Amanda; Leonardo, Eduardo David; Samuels, Benjamin A.; Hen, Rene; Wong, Erik; Nesbitt, Addie May I.; Alter, Mark 2014 Articles Dentate gyrusFluoxetineGenetic regulationAntidepressants--EffectivenessNeurosciencesMolecular biologyMedical sciences
3. Serotonin/Dopamine Interactions in a Hyperactive Mouse: Reduced Serotonin Receptor 1B Activity Reverses Effects of Dopamine Transporter Knockout Sora, Ichiro; Hen, Rene; Uhl, George R.; Hall, Frank Scott 2014 Articles DopamineCocaine--Physiological effectDrug interactionsSerotonin--ReceptorsNeurosciencesMolecular biologyMedical sciences
4. Adult neurogenesis modifies excitability of the dentate gyrus Ikrar, Taruna; Guo, Nannan; He, Kaiwen; Besnard, Antoine; Levinson, Sally; Hill, Alexis; Lee, Hey-Kyoung; Hen, Rene; Xu, Xiangmin; Sahay, Amar 2013 Articles Dentate gyrusPattern formation (Biology)Developmental neurobiologyNeurosciencesMolecular biology
5. A method for biomarker measurements in peripheral blood mononuclear cells isolated from anxious and depressed mice: β-arrestin 1 protein levels in depression and treatment Mendez-David, Indira; El-Al, Zeina; Hen, Rene; Falissard, Bruno; Corruble, Emmanuelle; Gardier, Alain M.; Kerdine-Römer, Saadia; David, Denis J. 2013 Articles ArrestinsDepression, Mental--TreatmentBiochemical markersNeurosciencesMolecular biologyMental health
6. Expanding the Repertoire of Optogenetically Targeted Cells with an Enhanced Gene Expression System Tanaka, Kenji F.; Matsui, Ko; Sasaki, Takuya; Sano, Hiromi; Sugio, Shouta; Fan, Kai; Hen, Rene; Nakai, Junichi; Yanagawa, Yuchio; Hasuwa, Hidetoshi; Okabe, Masaru; Deisseroth, Karl; Ikenaka, Kazuhiro; Yamanaka, Akihiro 2012 Articles TetracyclineOptogeneticsGene expressionNeurosciencesMolecular biologyCytology
7. Autism and Increased Paternal Age Related Changes in Global Levels of Gene Expression Regulation Alter, Mark D.; Kharkar, Rutwik; Ramsey, Keri E.; Craig, David W.; Melmed, Raun D.; Grebe, Theresa A.; Bay, R. Curtis; Ober-Reynolds, Sharman; Kirwan, Janet; Jones, Josh J.; Turner, J. Blake; Hen, Rene; Stephan, Dietrich A. 2011 Articles Autism--EtiologyDNA microarrays--Data processingGenetic regulationGeneticsMolecular biologyMedical sciences
8. Necessity of Hippocampal Neurogenesis for the Therapeutic Action of Antidepressants in Adult Nonhuman Primates Perera, Tarique D.; Dwork, Andrew Jay; Keegan, Kathryn A.; Thirumangalakudi, Lakshmi; Lipira, Cecilia M.; Joyce, Niamh; Lange, Christopher; Higley, J. Dee; Rosoklija, Gorazd B.; Hen, Rene; Sackeim, Harold A.; Coplan, Jeremy D. 2011 Articles FluoxetinePrimates as laboratory animalsDepression, Mental--ResearchDevelopmental neurobiologyNeurosciencesMolecular biologyMental health
9. Hyperfunction of Muscarinic Receptor Maintains Long-Term Memory in 5-HT4 Receptor Knock-Out Mice Segu, Luis; Dumuis, Aline; Berrard, Sylvie; Bockaert, Joël; Buhot, Marie-Christine; Compan, Valérie; Hen, Rene; Lecomte, Marie-José; Wolff, Mathieu; Santamaria, Julie 2010 Articles Muscarinic receptorsSerotonin--ReceptorsHippocampus (Brain)Long-term memoryMolecular biologyMedical sciencesNeurosciences