Academic Commons

Articles

Increasing Evidence for the Use of Sodium Oxybate in Multi-Drug- Resistant Lance–Adams Syndrome

Riboldi, Giulietta M.; Frucht, Steven J.

Background: Treatment of posthypoxic myoclonus (PHM) can be a challenge in patients not responsive to first-line medications. PMH is a rare condition that has a dramatic impact on patients’ quality of life. Refractory cases are not uncommon.

Case Report: We report a patient with PHM non-responsive to conventional treatments who showed a dramatic improvement with sodium oxybate (SBX). Cases of PHM treated with SBX reported in the literature were reviewed.

Discussion: Resting and stimulus-induced myoclonus respond robustly to SBX, with significant improvement in patients’ quality of life. SBX may be considered in patients with PHM resistant to first-line medications.

Files

  • thumnail for 642-Article Text-15063-1-10-20190617.pdf 642-Article Text-15063-1-10-20190617.pdf application/pdf 491 KB Download File

Also Published In

Title
Tremor and Other Hyperkinetic Movements
DOI
https://doi.org/10.7916/d8-rnsh-c024

More About This Work

Academic Units
Center for Parkinson's Disease and Other Movement Disorders
Published Here
December 10, 2019