Academic Commons

Articles

How Should We Treat Depression in Patients with Cardiovascular Disease?

Kronish, Ian M.; Krupka, David; Davidson, Karina W.

Among patients with cardiovascular disease (CVD), depression is highly prevalent and is associated with worse cardiovascular prognosis and lower quality of life. Treatments for depression in CVD patients produce modest, but clinically significant reductions in depressive symptoms and show promise for improving cardiovascular prognosis. While tricyclics should generally be avoided, antidepressants from multiple other classes appear to be safe in cardiac patients. A strategy of engaging patients in choosing medications or psychotherapy and then intensifying treatment to therapeutic goal appears to be more effective at reducing depression than single mode interventions. Recommendations for screening all CVD patients for depression may be premature given increased costs associated with screening and gaps in knowledge about the risk-benefit ratio of depression treatment in mild and moderately depressed patients.

Files

  • thumnail for Kronish_Dial_Cardiovasc_Med_2012_PMC.pdf Kronish_Dial_Cardiovasc_Med_2012_PMC.pdf application/pdf 380 KB Download File

Also Published In

Title
Dialogues in cardiovascular medicine

More About This Work

Academic Units
Center for Behavioral Cardiovascular Health
Publisher
Servier International Medical Publishing
Published Here
May 2, 2016
Academic Commons provides global access to research and scholarship produced at Columbia University, Barnard College, Teachers College, Union Theological Seminary and Jewish Theological Seminary. Academic Commons is managed by the Columbia University Libraries.