2012 Presentations (Communicative Events)

Amplitude modulated photostimulation for probing neuronal network dynamics

Potter, Steve; Fong, Ming-fai; Newman, Jonathan; Tchumatchenko, Tatjana

Sensory input arrives in the cortex in the form of dynamic synaptic currents to populations of neurons. How cortical neurons encode and transmit these inputs ultimately determines the cognitive and behavioral response of the animal. Therefore, a number of theoretical studies have attempted to explain the cortical population response in model neuronal networks [1]. Yet, there are few experimental platforms for studying the dynamical rate responses in large living networks that match the manipulability of computational models. As a result, most experimental studies examining cortical input response properties are confined to independent or single neurons, e.g.