HomeHome

Depressive Symptoms and All-Cause Mortality in Unstable Angina Pectoris (from the Coronary Psychosocial Evaluation Studies [COPES])

William Whang; Daichi Shimbo; Ian M. Kronish; W. Lane Duvall; Howard Julien; Padmini Iyer; Matthew M. Burg; Karina W. Davidson

Title:
Depressive Symptoms and All-Cause Mortality in Unstable Angina Pectoris (from the Coronary Psychosocial Evaluation Studies [COPES])
Author(s):
Whang, William
Shimbo, Daichi
Kronish, Ian M.
Duvall, W. Lane
Julien, Howard
Iyer, Padmini
Burg, Matthew M.
Davidson, Karina W.
Date:
Type:
Articles
Department(s):
Center for Behavioral Cardiovascular Health
Medicine
Volume:
106
Persistent URL:
Book/Journal Title:
American Journal of Cardiology
Publisher:
Elsevier
Abstract:
Although depression is clearly associated with increased mortality after acute myocardial infarction, there is a paucity of data examining the impact of depression on patients with unstable angina (UA). We analyzed the relation between depressive symptoms and all-cause mortality in patients with UA who were enrolled in a prospective multicenter study of depression and acute coronary syndrome (ACS). Depressive symptoms were measured with the Beck Depression Inventory (BDI) within 1 week of the ACS event, and patients were selected for a BDI score 0 to 4 or ≥10. Our sample included 209 patients with UA, with 104 (50%) having a BDI score ≥10. Proportional hazards analyses adjusted for variables including left ventricular ejection fraction, Global Registry of Acute Coronary Events risk score, and Charlson co-morbidity index. In multivariable analyses, a BDI score ≥10 was associated with increased risk of 42-month all-cause mortality (hazard ratio 2.04, 95% confidence interval 1.20 to 3.46, p = 0.008) compared to a BDI score 0 to 4. In conclusion, our results confirm and extend previous evidence linking depression to worse outcomes in UA and suggest that interventions that address depression may be worth examining across the spectrum of risk in ACS.
Subject(s):
Depression, Mental
Angina pectoris
Myocardial infarction--Psychological aspects
Epidemiology
Medical sciences
Mental health
Publisher DOI:
https://doi.org/10.1016/j.amjcard.2010.06.015
Item views
282
Metadata:
text | xml
Suggested Citation:
William Whang, Daichi Shimbo, Ian M. Kronish, W. Lane Duvall, Howard Julien, Padmini Iyer, Matthew M. Burg, Karina W. Davidson, , Depressive Symptoms and All-Cause Mortality in Unstable Angina Pectoris (from the Coronary Psychosocial Evaluation Studies [COPES]), Columbia University Academic Commons, .

Columbia University Libraries | Policies | FAQ