Angiogenesis and Ovarian Function
- Angiogenesis and Ovarian Function
- Douglas, Nataki C.
Nakhuda, Gary S.
Sauer, Mark V.
Zimmermann, Ralf C.
- Obstetrics and Gynecology
- Persistent URL:
- Book/Journal Title:
- Journal für Fertilität und Reproduktion
- Ovarian follicle development and corpus luteum formation involves recurrent, regulated, and self-limited angiogenesis. In rodent and non-human primate models it was shown that the VEGF/VEGF receptor 2 signal transduction pathway is of critical importance for ovarian angiogenesis. Clinically manipulation of this pathway might be helpful in finding new treatment methods for ovarian cancer, ovarian hyperstimulation syndrome, polycystic ovarian disease, endometriosis, as well as new, non-hormonal contraceptive approaches.
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- Suggested Citation:
- Nataki C. Douglas, Gary S. Nakhuda, Mark V. Sauer, Ralf C. Zimmermann, 2005, Angiogenesis and Ovarian Function, Columbia University Academic Commons, https://doi.org/10.7916/D81R7174.