Angiogenesis and Ovarian Function Douglas Nataki C. author Columbia University. Obstetrics and Gynecology Nakhuda Gary S. author Columbia University. Obstetrics and Gynecology Sauer Mark V. author Columbia University. Obstetrics and Gynecology Zimmermann Ralf C. author Columbia University. Obstetrics and Gynecology Columbia University. Obstetrics and Gynecology originator text Articles 2005 English Ovarian follicle development and corpus luteum formation involves recurrent, regulated, and self-limited angiogenesis. In rodent and non-human primate models it was shown that the VEGF/VEGF receptor 2 signal transduction pathway is of critical importance for ovarian angiogenesis. Clinically manipulation of this pathway might be helpful in finding new treatment methods for ovarian cancer, ovarian hyperstimulation syndrome, polycystic ovarian disease, endometriosis, as well as new, non-hormonal contraceptive approaches. Obstetrics and gynecology Journal für Fertilität und Reproduktion 14 5 7 15 2005 http://hdl.handle.net/10022/AC:P:14453 NNC NNC 2012-08-20 15:26:19 -0400 2012-08-20 15:35:42 -0400 8473 eng