Angiogenesis and Ovarian Function
Nataki C. Douglas; Gary S. Nakhuda; Mark V. Sauer; Ralf C. Zimmermann
- Angiogenesis and Ovarian Function
Douglas, Nataki C.
Nakhuda, Gary S.
Sauer, Mark V.
Zimmermann, Ralf C.
- Obstetrics and Gynecology
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- Book/Journal Title:
- Journal für Fertilität und Reproduktion
- Ovarian follicle development and corpus luteum formation involves recurrent, regulated, and self-limited angiogenesis. In rodent and non-human primate models it was shown that the VEGF/VEGF receptor 2 signal transduction pathway is of critical importance for ovarian angiogenesis. Clinically manipulation of this pathway might be helpful in finding new treatment methods for ovarian cancer, ovarian hyperstimulation syndrome, polycystic ovarian disease, endometriosis, as well as new, non-hormonal contraceptive approaches.
- Obstetrics and gynecology
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